Evidence map›Paper›PMID 35693822›Full record

ArticleFrontiers in immunology2022

Metabolic Reprogramming Mediates Delayed Apoptosis of Human Neutrophils Infected With

Samantha J Krysa, Lee-Ann H Allen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Metabolic Control of Immunity-Unveiling Neutrophil Mechanisms.Advances in experimental medicine and biology · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Frontiers in immunology · 2025
    Article
  8. Article
  9. Review
  10. Activation induces shift in nutrient utilization that differentially impacts cell functions in human neutrophils.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Neutrophil Survival Signaling DuringFrontiers in cellular and infection microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Samantha J KrysaInflammation Program, University of Iowa, Iowa City, IA, United States.
Lee-Ann H AllenInflammation Program, University of Iowa, Iowa City, IA, United States.
University of Iowa · USUniversity of Missouri · US

Funding

Neutrophil Plasticity and H. pylori PathogenesisR01AI119965 · NIAID · UNIVERSITY OF MISSOURI-COLUMBIA · PI ALLEN, LEE-ANN H · 2016 to 2020
$2.1M
Francisella tularensis reprograms human neutrophilsR21AI137468 · NIAID · UNIVERSITY OF IOWA · PI ALLEN, LEE-ANN H · 2018 to 2018
$229k
Dysregulation of the inflammatory response by Francisella tularensisI01BX002108 · VA · IOWA CITY VA MEDICAL CENTER · PI ALLEN, LEE-ANN H · 2013 to 2023
–
BLRD VA I01 BX002108NIAID NIH HHS R01 AI119965NIAID NIH HHS R21 AI137468
6 · The paper itself

Abstract

Neutrophils (polymorphonuclear leukocytes, PMNs) have a distinctively short lifespan, and tight regulation of cell survival and death is imperative for their normal function. We demonstrated previously that

Indexed as

Francisella tularensisTularemiaApoptosisGlucoseGlycogenHumansNeutrophilsGlucoseGlycogenapoptosisFrancisella tularensisglycogenglycolysisimmunometabolismneutrophils (PMNs)

Identifiers

PMID35693822
PMCPMC9174434
OpenAlexW4281489377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.