Evidence map›Paper›PMID 35693809›Full record

ArticleFrontiers in immunology2022

Negative Regulator Nlrc3-like Maintain the Balanced Innate Immune Response During Mycobacterial Infection in Zebrafish.

Liangfei Niu, Geyang Luo, Rui Liang, Chenli Qiu, Jianwei Yang, Lingling Xie, Kaile Zhang, Yu Tian, Decheng Wang, Shu Song and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. A granulin-positive macrophage subtype in mycobacterial granulomas alleviates tissue damage by limiting excessive inflammation.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. Article
  6. Frontiers in tuberculosis · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Liangfei NiuShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Geyang LuoShanghai Public Health Clinical Center, Key Laboratory of Medical Molecular Virology [Ministry of Education (MOE)/National Health Commission (NHC)/Chinese Academy of Medical Sciences (CAMS)], School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, China.
Rui LiangShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Chenli QiuShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Jianwei YangShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Lingling XieShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Kaile ZhangShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Yu TianShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Decheng WangMedical College, China Three Gorges University, Yichang, China.
Shu SongShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Howard E TakiffDepartment of Tuberculosis Control and Prevention, Shenzhen Nanshan Centre for Chronic Disease Control, Shenzhen, China.
Ka-Wing WongShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Xiaoyong FanShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Qian GaoShanghai Public Health Clinical Center, Key Laboratory of Medical Molecular Virology [Ministry of Education (MOE)/National Health Commission (NHC)/Chinese Academy of Medical Sciences (CAMS)], School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, China.
Bo YanShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Shanghai Public Health Clinical Center · CNBengbu Medical College · CNChina Three Gorges University · CNShenzhen Nanshan Center for Chronic Disease Control · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The NOD-like receptors (NLRs) have been shown to be involved in infection and autoinflammatory disease. Previously, we identified a zebrafish NLR,

Indexed as

Mycobacterium Infections, NontuberculousZebrafishAnimalsHumansImmunity, InnateInflammasomesIntercellular Signaling Peptides and ProteinsIntracellular Signaling Peptides and ProteinsNLR ProteinsZebrafish ProteinsInflammasomesIntercellular Signaling Peptides and ProteinsIntracellular Signaling Peptides and Proteinsnlrc3l protein, zebrafishNLR ProteinsZebrafish Proteinsinflammasomeinnate immunitymacrophagemycobacterial infectionneutrophilNLR

Identifiers

PMID35693809
PMCPMC9174460
OpenAlexW4281486464

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.