Evidence map›Paper›PMID 35693801›Full record

ReviewFrontiers in immunology2022

Conventional Type 1 Dendritic Cells in Intestinal Immune Homeostasis.

Izumi Sasaki, Takashi Kato, Hiroaki Hemmi, Yuri Fukuda-Ohta, Naoko Wakaki-Nishiyama, Asumi Yamamoto, Tsuneyasu Kaisho

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Article
  3. Type 1 and CD103European journal of immunology · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Thymic Dendritic Cells Revisited.Immunological reviews · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. CD4Immunity · 2024
    Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Izumi SasakiDepartment of Immunology, Institute for Advanced Medicine, Wakayama Medical University, Wakayama, Japan.
Takashi KatoDepartment of Immunology, Institute for Advanced Medicine, Wakayama Medical University, Wakayama, Japan.
Hiroaki HemmiDepartment of Immunology, Institute for Advanced Medicine, Wakayama Medical University, Wakayama, Japan.
Yuri Fukuda-OhtaDepartment of Immunology, Institute for Advanced Medicine, Wakayama Medical University, Wakayama, Japan.
Naoko Wakaki-NishiyamaDepartment of Immunology, Institute for Advanced Medicine, Wakayama Medical University, Wakayama, Japan.
Asumi YamamotoDepartment of Immunology, Institute for Advanced Medicine, Wakayama Medical University, Wakayama, Japan.
Tsuneyasu KaishoDepartment of Immunology, Institute for Advanced Medicine, Wakayama Medical University, Wakayama, Japan.
Wakayama Medical University · JPOkayama University of Science · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dendritic cells (DC) play critical roles in linking innate and adaptive immunity. DC are heterogenous and there are subsets with various distinct functions. One DC subset, conventional type 1 DC (cDC1), can be defined by expression of CD8α/CD103 in mice and CD141 in humans, or by expression of a chemokine receptor, XCR1, which is a conserved marker in both mice and human. cDC1 are characterized by high ability to ingest dying cells and to cross-present antigens for generating cytotoxic CD8 T cell responses. Through these activities, cDC1 play crucial roles in immune responses against infectious pathogens or tumors. Meanwhile, cDC1 involvement in homeostatic situations is not fully understood. Analyses by using mutant mice, in which cDC1 are ablated

Indexed as

Cross-PrimingDendritic CellsAnimalsCD8-Positive T-LymphocytesHomeostasisMiceReceptors, ChemokineReceptors, Chemokinedendritic cellgene targetingintestinesubsetT cellXCR1

Identifiers

PMID35693801
PMCPMC9184449
OpenAlexW4281668291

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.