ReviewFrontiers in immunology2022
Role of Basophils in a Broad Spectrum of Disorders.
Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Illuminating Immunity: A Systematic Review of Immune Cell Autofluorescence.Journal of biophotonics · 2025Pooled it
- The Effect of Low-Dose Acetylsalicylic Acid on Cellular Immune Responses to Experimental Sleep Restriction in Healthy Humans.Neuroimmunomodulation · 2026Trial
- Haematological and biochemical profiling combined with HRAMS-based metabolomics reveals the potential biomarkers ofRSC advances · 2026Article
- Basophil Extracellular Traps in Immunity and Disease.Cancers · 2026Review
- Selective Hematological Profiles in Drug-Naïve Early Autism: Clinical and Developmental Correlates.Biomedicines · 2026Article
- Clinical and Immunovirological Characteristics Associated with Cardiovascular Dysautonomia in Long COVID.Journal of clinical medicine · 2026Article
- A foundational model encodes deep phenotyping data and enables diverse downstream applications.NPJ digital medicine · 2026Article
- Basophils drive the resolution and promote wound healing in adult and aged mice.The Journal of experimental medicine · 2026Article
- Three-year risk prediction of aortic stenosis using routine medical records: derivation and validation in 919 954 individuals from two cohorts.European heart journal. Digital health · 2026Article
- Article
- Basophils in atopic dermatitis: Immunologic roles and clinical implications.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2026Review
- Machine Learning Prediction of Poor Flexion-Extension Outcome After Open Elbow Arthrolysis: Identifying Individual Predisposition Using Clinical and Laboratory Indicators.Orthopaedic journal of sports medicine · 2025Article
- The dual role of extracellular vesicles derived from animal and human immune cells: A systematic review.Journal of advanced veterinary and animal research · 2025Review
- Constructing a prediction model for acute pancreatitis severity based on liquid neural network.Scientific reports · 2025Article
- Arginine metabolism in myeloid cells in health and disease.Seminars in immunopathology · 2025Review
- Thymic stromal lymphopoietin-activated basophil promotes lung inflammation in mouse atopic march model.Frontiers in immunology · 2025Article
- Non-Malignant Granulocyte and Monocyte Disorders: An Update.British journal of biomedical science · 2025Review
- A Two-Sample Mendelian Randomization Study of Basophil Count and Risk of Gestational Diabetes Mellitus.International journal of women's health · 2025Article
- Carbonic anhydrase 8 regulates basophil activation and interleukin 4 production.Frontiers in immunology · 2025Article
- Efficacy and safety of intravitreal anti-VEGF for myopic choroidal neovascularization.International journal of ophthalmology · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Basophils are the rarest granulocytes and have long been overlooked in immunological research due to their rarity and similarities with tissue-resident mast cells. In the last two decades, non-redundant functions of basophils have been clarified or implicated in a broad spectrum of immune responses, particularly by virtue of the development of novel analytical tools for basophils. Basophils infiltrate inflamed tissues of patients with various disorders, even though they circulate in the bloodstream under homeostatic conditions. Depletion of basophils results in the amelioration or exaggeration of inflammation, depending on models of disease, indicating basophils can play either beneficial or deleterious roles in a context-dependent manner. In this review, we summarize the recent findings of basophil pathophysiology under various conditions in mice and humans, including allergy, autoimmunity, tumors, tissue repair, fibrosis, and COVID-19. Further mechanistic studies on basophil biology could lead to the identification of novel biomarkers or therapeutic targets in a broad range of diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.