Evidence map›Paper›PMID 35693767›Full record

ArticleFrontiers in immunology2022

C/EBPα Epigenetically Modulates

Huan Qu, Qiufang Zong, Haifei Wang, Shenglong Wu, Demin Cai, Wenbin Bao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Hepatic Anti-Oxidative GenesAntioxidants (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Huan QuCollege of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Qiufang ZongCollege of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Haifei WangCollege of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Shenglong WuCollege of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Demin CaiCollege of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Wenbin BaoCollege of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Yangzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Porcine epidemic diarrhea virus (PEDV) is an emerging coronavirus which causes acute diarrhea and destroys gastrointestinal barrier function in neonatal pigs. Trefoil factor 1 (TFF1) is a protective peptide for maintaining the integrity of gastrointestinal mucosa and reducing intestinal inflammation. However, its role in protecting intestinal epithelium against PEDV infection is still unclear. In this study, we discovered that TFF1 expression was activated in the jejunum of pigs with PEDV infection and TFF1 is required for the growth of porcine intestinal epithelial cells. For instance, inhibited cell proliferation and cell arrest were observed when

Indexed as

CoronavirusCoronavirus InfectionsPorcine epidemic diarrhea virusAnimalsCCAAT-Enhancer-Binding Protein-alphaEpigenesis, GeneticInflammationJejunumMethylationSwineTrefoil Factor-1CCAAT-Enhancer-Binding Protein-alphaTrefoil Factor-1C/EBPαcoronavirusDNA methylationintestinal epithelial barrierporcine epidemic diarrhea virusTFF1

Identifiers

PMID35693767
PMCPMC9174463
OpenAlexW4281479856

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.