Evidence map›Paper›PMID 35693761›Full record

ReviewFrontiers in immunology2022

From Insect Bites to a Skin Autoimmune Disease: A Conceivable Pathway to Endemic Pemphigus Foliaceus.

Ning Li, Valeria Aoki, Zhi Liu, Phillip Prisayanh, Jesus G Valenzuela, Luis A Diaz

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Ultrastructural skin alterations of healthy subjects withJournal of translational autoimmunity · 2023
    Article
  5. Review
  6. Article
  7. Molecular Mimicry between SARS-CoV-2 and Human Endocrinocytes: A Prerequisite of Post-COVID-19 Endocrine Autoimmunity?Pathophysiology : the official journal of the International Society for Pathophysiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Ning LiDepartment of Dermatology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Valeria AokiDepartment of Dermatology, Faculdade de Medicina Facultade de Medicina, Universidade de Sao Paulo (FMUSP), Universidade de Sao Paulo, Sao Paulo, Brazil.
Zhi LiuDepartment of Dermatology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Phillip PrisayanhDepartment of Dermatology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Jesus G ValenzuelaVector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, United States.
Luis A DiazDepartment of Dermatology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
University of North Carolina at Chapel Hill · USUniversidade de São Paulo · BRVector (United States) · US

Funding

Re-Entry Supplement: Investigation of Oral Microbial Enzymes for the Detection and Treatment of Periodontal DiseaseUL1TR002489 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, SHAHEEN, NICHOLAS J · 2018 to 2022
$48.6M
Molecular approaches to understand vector-host and vector-pathogen interactionsZIAAI000932 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI VALENZUELA, JESUS · 2009 to 2025
$23.1M
ETIOLOGY AND PATHOGENESIS OF PEMPHIGUSR01AR032599 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DIAZ, LUIS A. · 1987 to 2017
$5.2M
IMMUNOPATHOGENESIS OF BULLOUS PEMPHIGOIDR01AI040768 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LIU, ZHI · 2001 to 2016
$4.1M
The Mechanism of IVIG Action in PemphigusR01AI061430 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LIU, ZHI · 2004 to 2006
$999k
NIAID NIH HHS R01 AI040768NIAID NIH HHS R01 AI061430NIAMS NIH HHS R01 AR032599
6 · The paper itself

Abstract

In the endemic variants of pemphigus foliaceus (PF), in Brazil and Tunisia, patients generate pathogenic IgG4 anti-desmoglein 1 autoantibodies. Additionally, these patients possess antibodies against salivary proteins from sand flies that react with Dsg1, which may lead to skin disease in susceptible individuals living in endemic areas. This minireview focuses on recent studies highlighting the possible role of salivary proteins from

Indexed as

Autoimmune DiseasesInsect Bites and StingsPemphigusPsychodidaeAnimalsDesmoglein 1HumansDesmoglein 1autoantibodiesdesmoglein 1fogo selvagem (FS)sandfliesTunisian pemphigus foliaceus

Identifiers

PMID35693761
PMCPMC9186141
OpenAlexW4281622569

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.