Evidence map›Paper›PMID 35693745›Full record

ArticleInternational journal of medical sciences2022

Liquid Enteral Nutrients Alter the Pharmacokinetics of Orally Administered Carbamazepine in Rats.

Yoko Urashima, Honami Kobayashi, Kana Yamamoto, Kazuki Matsushita, Kazuya Urashima, Masahiko Tsujikawa, Kaoru Suzuki, Kazumi Kurachi, Masami Nishihara, Masashi Neo and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Yoko UrashimaLaboratory of Clinical Pharmaceutics, Faculty of Pharmacy, Osaka Ohtani University, Osaka, Japan.
Honami KobayashiLaboratory of Clinical Pharmaceutics, Faculty of Pharmacy, Osaka Ohtani University, Osaka, Japan.
Kana YamamotoLaboratory of Clinical Pharmaceutics, Faculty of Pharmacy, Osaka Ohtani University, Osaka, Japan.
Kazuki MatsushitaLaboratory of Clinical Pharmaceutics, Faculty of Pharmacy, Osaka Ohtani University, Osaka, Japan.
Kazuya UrashimaDepartment of Pharmacy, Japan Community Health Care Organization Hoshigaoka Medical Center, Osaka, Japan.
Masahiko TsujikawaDepartment of Pharmacy, Japan Community Health Care Organization Osaka Hospital, Osaka, Japan.
Kaoru SuzukiDepartment of Pharmacy, Osaka Medical and Pharmaceutical University Hospital, Osaka, Japan.
Kazumi KurachiDepartment of Pharmacy, Osaka Medical and Pharmaceutical University Hospital, Osaka, Japan.
Masami NishiharaDepartment of Pharmacy, Osaka Medical and Pharmaceutical University Hospital, Osaka, Japan.
Masashi NeoDepartment of Pharmacy, Osaka Medical and Pharmaceutical University Hospital, Osaka, Japan.
Michiaki MyotokuLaboratory of Practical Pharmacy and Pharmaceutical Care, Faculty of Pharmacy, Osaka Ohtani University, Osaka, Japan.
Takuro KoboriLaboratory of Clinical Pharmaceutics, Faculty of Pharmacy, Osaka Ohtani University, Osaka, Japan.
Tokio ObataLaboratory of Clinical Pharmaceutics, Faculty of Pharmacy, Osaka Ohtani University, Osaka, Japan.
Osaka Ohtani University · JPOsaka University of Pharmaceutical Sciences · JPHoshigaoka Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The interaction between enteral nutrients (ENs) and drugs co-administered through a nasogastric (NG) tube reportedly affects the absorption and resultant plasma concentrations of the respective drugs. However, the gastrointestinal absorption of carbamazepine (CBZ), an antiepileptic drug, co-administered with liquid ENs through an NG tube has not been clarified. In this study, we measured the recovery rate (%) of CBZ (Tegretol

Indexed as

AnticonvulsantsCarbamazepineAdministration, OralAnimalsArea Under CurveNutrientsRatsAnticonvulsantsCarbamazepineNutrientsantiepileptic drugCarbamazepineenteral nutrientgastrointestinal absorptionnasogastric tube

Identifiers

PMID35693745
PMCPMC9149647
OpenAlexW4285236873

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.