Evidence map›Paper›PMID 35693699›Full record

ArticleOxidative medicine and cellular longevity2022

Protective Effects of

Jingjing Li, Yanfen Cheng, Renkai Li, Xiaoping Wu, Chengwen Zheng, Polly Ho-Ting Shiu, Jacqueline Cho-Ki Chan, Panthakarn Rangsinth, Conghui Liu, Susan Wai-Sum Leung and 6 more

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Retracted: Protective Effects ofOxidative medicine and cellular longevity · 2023
    Article
  9. Molecules (Basel, Switzerland) · 2022
    Article
  10. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 3 countries.

Jingjing LiDepartment of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.ORCID https://orcid.org/0000-0003-3636-0537
Yanfen ChengState Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Renkai LiDepartment of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Xiaoping WuDepartment of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Chengwen ZhengDepartment of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Polly Ho-Ting ShiuDepartment of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Jacqueline Cho-Ki ChanDepartment of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Panthakarn RangsinthDepartment of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Conghui LiuDepartment of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Susan Wai-Sum LeungDepartment of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
Simon Ming-Yuen LeeState Key Laboratory of Quality Research in Chinese Medicine and Institute of Chinese Medical Sciences, University of Macau, Macao SAR, China.
Chen ZhangState Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Chaomei FuState Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Jinming ZhangState Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Timothy Man-Yau CheungTian Ran Healthcare Limited, Hong Kong, China.
George Pak-Heng LeungDepartment of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.ORCID https://orcid.org/0000-0003-3529-9367
Chinese University of Hong Kong · HKChengdu University of Traditional Chinese Medicine · CNHong Kong Polytechnic University · HKUniversity of Macau · MO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical outcomes for doxorubicin (Dox) are limited by its cardiotoxicity but a combination of Dox and agents with cardioprotective activities is an effective strategy to improve its therapeutic outcome. Natural products provide abundant resources to search for novel cardioprotective agents.

Indexed as

CardiotoxicityNF-E2-Related Factor 2AnimalsApoptosisDoxorubicinGanodermaHeme Oxygenase-1Heme Oxygenase (Decyclizing)Membrane ProteinsMiceMitochondriaMyocytes, CardiacOxidative StressPolyporaceaeProto-Oncogene Proteins c-aktRatsDoxorubicinHeme Oxygenase-1Heme Oxygenase (Decyclizing)Hmox1 protein, mouseHmox1 protein, ratMembrane ProteinsmTOR protein, ratNF-E2-Related Factor 2Proto-Oncogene Proteins c-aktTOR Serine-Threonine Kinases

Identifiers

PMID35693699
PMCPMC9177334
OpenAlexW4281762503

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.