ArticleJournal of thyroid research2022
Iodine Deficiency in Patients with Hypothyroidism: A Pilot Study.
Article in Journal of thyroid research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The trial behind it
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Who cites it
2 citing papers in PubMed, 3 citations in OpenAlex.
- Association between serum iodine and thyroid function in Malagasy adults: a cross-sectional study in a tertiary-level hospital in Antananarivo, Madagascar.The Libyan journal of medicine · 2026Article
- Thyroid function after menopause: is there any concern in thyroidology?Revista da Associacao Medica Brasileira (1992) · 2024Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Worldwide, 21 countries have insufficient iodine in their diets. Persistent iodine deficiency may result in hypothyroidism. The aim of this study is to determine whether iodine measurements can be used to determine the prevalence of iodine deficiency in patients with (subclinical) hypothyroidism compared to a control group. Design: A prospective cohort pilot study was performed at the Internal Medicine Outpatient Clinic of Isala, a large teaching hospital in Zwolle, the Netherlands. Results: According to UIE and UIC measurements, 54.2% of hypothyroid patients were iodine-deficient compared to 41.7-45.8% in the control group. According to the I : Cr measurement 91.7% of hypothyroid patients were iodine-deficient compared to 87.5% in the control group. No significant difference was seen between the two groups. No correlation was found between thyroid-stimulating hormone (TSH) level and iodine deficiency. Conclusions: Iodine deficiency is prevalent in both hypothyroid patients and euthyroid patients. Because there is no significant difference between the groups, a single 24-hour urine or spot urine sample to determine UIC, UIE, and I : Cr, seems not suitable to determine iodine status in an individual participant.
Identifiers
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Registered trials
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