Evidence map›Paper›PMID 35693058›Full record

ArticleLe infezioni in medicina2022

Higher viral load of Epstein-Barr virus in gastric cancer compared with non-cancerous gastroduodenal tissues.

Arghavan Zebardast, Maryam Pazhoohan, Azadeh Yazdani Cherati, Maryam Salehi, Saghar Saber Amoli, Yousef Yahyapour, Mohammad Ranaee, Javad Shokri Shirvani, Farzin Sadeghi

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Article in Le infezioni in medicina, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Arghavan ZebardastStudents Research Committee, Babol University of Medical Sciences, Babol, Iran.
Maryam PazhoohanStudents Research Committee, Babol University of Medical Sciences, Babol, Iran.
Azadeh Yazdani CheratiStudents Research Committee, Babol University of Medical Sciences, Babol, Iran.
Maryam SalehiStudents Research Committee, Babol University of Medical Sciences, Babol, Iran.
Saghar Saber AmoliDepartment of Microbiology, School of Medicine, Babol University of Medical Sciences, Babol, Iran.
Yousef YahyapourInfectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol; University of Medical Sciences, Babol, Iran.
Mohammad RanaeeDepartment of Pathology, School of Medicine, Babol University of Medical Sciences, Babol, Iran.
Javad Shokri ShirvaniDepartment of Internal Medicine, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran.
Farzin SadeghiCancer Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Epstein-Barr Virus (EBV)-associated gastric cancer is a distinct molecular subtype of gastrointestinal carcinomas as defined by the Cancer Genome Atlas. Methods: In the present study 237 samples from Iranian patients diagnosed with gastric cancer and gastroduodenal disease were retrospectively examined for EBV infection by quantitative Real-Time PCR. Results: Of the 237 samples tested, EBV DNA was detected in 37 samples (15.6%), in 13 of the 81 gastric cancer cases (16%), and 24 of the 156 non-cancerous samples (15.4%). The EBV infection rate was found higher in patients with gastric ulcer (35%) and duodenal ulcer (21.9%) compared to patients with gastric cancer (16%) and gastritis (19.6%). The EBV-encoded small RNA (EBER) copy number in the gastric cancer group (mean = 2.14×10 Conclusion: The higher number of copies of EBV-EBER in the gastric cancer group compared to the non-cancer group confirmed the possible role of EBV in inducing cancer.

Indexed as

cancerEpstein-Barr virusgastric cancergastroduodenal diseaseHelicobacter pylori

Identifiers

PMID35693058
PMCPMC9177184

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.