Evidence map›Paper›PMID 35692822›Full record

ArticleFrontiers in genetics2022

Fine Mapping of a Major Backfat QTL Reveals a Causal Regulatory Variant Affecting the

Haniel C Oliveira, Martijn F L Derks, Marcos S Lopes, Ole Madsen, Barbara Harlizius, Maren van Son, Eli H Grindflek, Marta Gòdia, Arne B Gjuvsland, Pamela Itajara Otto and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Haniel C OliveiraDepartment of Animal Science, Universidade Federal de Viçosa, Viçosa, Brazil.
Martijn F L DerksTopigs Norsvin Research Center, Beuningen, Netherlands.
Marcos S LopesTopigs Norsvin Research Center, Beuningen, Netherlands.
Ole MadsenAnimal Breeding and Genomics, Wageningen University & Research, Wageningen, Netherlands.
Barbara HarliziusTopigs Norsvin Research Center, Beuningen, Netherlands.
Maren van SonNorsvin SA, Hamar, Norway.
Eli H GrindflekNorsvin SA, Hamar, Norway.
Marta GòdiaAnimal Breeding and Genomics, Wageningen University & Research, Wageningen, Netherlands.
Arne B GjuvslandNorsvin SA, Hamar, Norway.
Pamela Itajara OttoDepartment of Animal Science, Universidade Federal de Santa Maria, Santa Maria, Brazil.
Martien A M GroenenAnimal Breeding and Genomics, Wageningen University & Research, Wageningen, Netherlands.
Simone E F GuimaraesDepartment of Animal Science, Universidade Federal de Viçosa, Viçosa, Brazil.
Wageningen University & Research · NLNorsvin (Norway) · NOTopigs Norsvin (Netherlands) · NLUniversidade Federal de Viçosa · BRUniversidade Federal de Santa Maria · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Backfat is an important trait in pork production, and it has been included in the breeding objectives of genetic companies for decades. Although adipose tissue is a good energy storage, excessive fat results in reduced efficiency and economical losses. A large QTL for backfat thickness on chromosome 5 is still segregating in different commercial pig breeds. We fine mapped this QTL region using a genome-wide association analysis (GWAS) with 133,358 genotyped animals from five commercial populations (Landrace, Pietrain, Large White, Synthetic, and Duroc) imputed to the porcine 660K SNP chip. The lead SNP was located at 5:66103958 (G/A) within the third intron of the

Indexed as

animal breedingbackfatfinemappingGWASpig genomics

Identifiers

PMID35692822
PMCPMC9180923
OpenAlexW4281487693

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.