Evidence map›Paper›PMID 35692773›Full record

ArticleFrontiers in oncology2022

Case Report:

Michelle Prasuhn, Josephine Christin Freitag, Sabine Lüken, Vinodh Kakkassery, Hartmut Merz, Almuth Caliebe, Malte Spielmann, Mahdy Ranjbar, Felix Rommel

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Michelle PrasuhnDepartment of Ophthalmology, University Hospital Schleswig-Holstein, University of Lübeck, Lübeck, Germany.
Josephine Christin FreitagDepartment of Ophthalmology, University Hospital Schleswig-Holstein, University of Lübeck, Lübeck, Germany.
Sabine LükenDepartment of Ophthalmology, University Hospital Schleswig-Holstein, University of Lübeck, Lübeck, Germany.
Vinodh KakkasseryDepartment of Ophthalmology, University Hospital Schleswig-Holstein, University of Lübeck, Lübeck, Germany.
Hartmut MerzHämatopathologie Lübeck, Reference Centre for Lymph Node Pathology andHematopathology, Lübeck, Germany.
Almuth CaliebeInstitute of Human Genetics, University Hospital of Schleswig-Holstein, University of Lübeck, Lübeck, Germany.
Malte SpielmannInstitute of Human Genetics, University Hospital of Schleswig-Holstein, University of Lübeck, Lübeck, Germany.
Mahdy RanjbarDepartment of Ophthalmology, University Hospital Schleswig-Holstein, University of Lübeck, Lübeck, Germany.
Felix RommelDepartment of Ophthalmology, University Hospital Schleswig-Holstein, University of Lübeck, Lübeck, Germany.
University of Lübeck · DEUniversity Hospital Schleswig-Holstein · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The molecular mechanisms for uveal ring melanoma are still unclear until today. In this case report, we describe a patient with a malignant uveal melanoma with exudative retinal detachment that had been treated with plaque brachytherapy, resulting in successful tumor regression. After 1 year, a ring-shaped recurrence with extraocular extension appeared, and the eye required enucleation. Histological and molecular genetic analyses revealed an epithelioid-cell-type melanoma with complete circumferential involvement of the ciliary body and, so far, unreported GNAQ and SF3B1 mutations in ring melanoma. Therefore, this report gives new genetic background information on this ocular tumor usually leading to enucleation.

Indexed as

brachytherapycase reportGNAQring melanomaSF3B1uveal melanoma

Identifiers

PMID35692773
PMCPMC9175007
OpenAlexW4281486555

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.