Evidence map›Paper›PMID 35692577›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2022

Phytochemical Characterization and Pharmacological Properties of Lichen Extracts from Cetrarioid Clade by Multivariate Analysis and Molecular Docking.

Isabel Ureña-Vacas, Elena González-Burgos, Simona De Vita, Padreep K Divakar, Giuseppe Bifulco, M Pilar Gómez-Serranillos

Abstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Isabel Ureña-VacasDepartment of Pharmacology, Pharmacognosy and Botany, Faculty of Pharmacy, Universidad Complutense de Madrid, Plaza Ramon y Cajal S/n, Ciudad Universitaria, Madrid 28040, Spain.ORCID https://orcid.org/0000-0003-0313-9465
Elena González-BurgosDepartment of Pharmacology, Pharmacognosy and Botany, Faculty of Pharmacy, Universidad Complutense de Madrid, Plaza Ramon y Cajal S/n, Ciudad Universitaria, Madrid 28040, Spain.ORCID https://orcid.org/0000-0003-2119-8768
Simona De VitaDepartment of Pharmacy, University of Salerno, Via Giovanni Paolo II 134, Fisciano (SA) 84084, Italy.ORCID https://orcid.org/0000-0002-8203-3580
Padreep K DivakarDepartment of Pharmacology, Pharmacognosy and Botany, Faculty of Pharmacy, Universidad Complutense de Madrid, Plaza Ramon y Cajal S/n, Ciudad Universitaria, Madrid 28040, Spain.ORCID https://orcid.org/0000-0002-0300-0124
Giuseppe BifulcoDepartment of Pharmacy, University of Salerno, Via Giovanni Paolo II 134, Fisciano (SA) 84084, Italy.ORCID https://orcid.org/0000-0002-1788-5170
M Pilar Gómez-SerranillosDepartment of Pharmacology, Pharmacognosy and Botany, Faculty of Pharmacy, Universidad Complutense de Madrid, Plaza Ramon y Cajal S/n, Ciudad Universitaria, Madrid 28040, Spain.ORCID https://orcid.org/0000-0002-9178-3420

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Lichens, due to the presence of own secondary metabolites such as depsidones and depsides, became a promising source of health-promoting organisms with pharmacological activities. However, lichens and their active compounds have been much less studied. Therefore, the present study aims to evaluate for the first time the antioxidant capacity and enzyme inhibitory activities of 14 lichen extracts belonging to cetrarioid clade in order to identify new natural products with potential pharmacological activity. Materials and Methods: In this study, an integrated strategy was applied combining multivariate statistical analysis (principal component analysis and hierarchical cluster analysis), phytochemical identification, activity evaluation ( Conclusions: Our results concluded that these species could be effective in the treatment of neurodegenerative diseases, being mandatory further investigation in cell culture and

Identifiers

PMID35692577
PMCPMC9187481

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.