Evidence map›Paper›PMID 35692566›Full record

ArticleCanada communicable disease report = Releve des maladies transmissibles au Canada2021

The hepatitis C epidemic in Canada: An overview of recent trends in surveillance, injection drug use, harm reduction and treatment.

Lillian Lourenço, Marian Kelly, Jill Tarasuk, Kyla Stairs, Maggie Bryson, Nashira Popovic, Josephine Aho

Open access · diamondAbstract read
In one paragraph

Article in Canada communicable disease report = Releve des maladies transmissibles au Canada, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Hepatitis C Screening: A Health Technology Assessment.Ontario health technology assessment series · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Review
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  19. Characterizing the cascade of care for hepatitis C virus infection among Status First Nations peoples in Ontario: a retrospective cohort study.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Lillian LourençoPublic Health Agency of Canada, Centre for Communicable Diseases and Infection Control, Ottawa, ON.
Marian KellyPublic Health Agency of Canada, Centre for Communicable Diseases and Infection Control, Ottawa, ON.
Jill TarasukPublic Health Agency of Canada, Centre for Communicable Diseases and Infection Control, Ottawa, ON.
Kyla StairsPublic Health Agency of Canada, Centre for Communicable Diseases and Infection Control, Ottawa, ON.
Maggie BrysonPublic Health Agency of Canada, Centre for Communicable Diseases and Infection Control, Ottawa, ON.
Nashira PopovicPublic Health Agency of Canada, Centre for Communicable Diseases and Infection Control, Ottawa, ON.
Josephine AhoPublic Health Agency of Canada, Centre for Communicable Diseases and Infection Control, Ottawa, ON.
Public Health Agency of Canada · CANational Centre for Infectious Diseases · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis C continues to be a significant public health concern in Canada, with the hepatitis C virus (HCV) responsible for more life-years lost than all other infectious diseases in Canada. An increase in reported hepatitis C infections was observed between 2014 and 2018. Here, we present changing epidemiological trends and discuss risk factors for hepatitis C acquisition in Canada that may have contributed to this increase in reported hepatitis C infections, focusing on injection drug use. We describe a decrease in the use of borrowed needles or syringes coupled with an increase in using other used injection drug use equipment. Also, an increased prevalence of injection drug use and use of prescription opioid and methamphetamine injection by people who inject drugs (PWID) may be increasing the risk of HCV acquisition. At the same time, while harm reduction coverage appears to have increased in Canada in recent years, gaps in access and coverage remain. We also consider how direct-acting antiviral (DAA) eligibility expansion may have affected hepatitis C rates from 2014 to 2018. Finally, we present new surveillance trends observed in 2019 and discuss how the coronavirus disease 2019 (COVID-19) pandemic may affect hepatitis C case counts from 2020 onwards. Continual efforts to i) enhance hepatitis C surveillance and ii) strengthen the reach, effectiveness, and adoption of hepatitis C prevention and treatment services across Canada are vital to reducing HCV transmission among PWID and achieving Canada's HCV elimination targets by 2030.

Indexed as

Canadian Drugs and Substances StrategyepidemiologyHCVneedle-and-syringe programspeople who inject drugsPWIDsubstance usesupervised consumption

Identifiers

PMID35692566
PMCPMC9126177
OpenAlexW4200447750

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.