ReviewFrontiers in medicine2022
A Review of the Diagnosis and Treatment of Limbal Stem Cell Deficiency.
Review in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 74 citations in OpenAlex.
- Comparative evaluation of autologous tissue-engineered ocular and oral mucosal tissue grafts- a prospective randomized controlled trial.BMC biotechnology · 2024Trial
- Simple oral mucosal epithelial transplantation (SOMET) for bilateral limbal stem cell deficiency in a patient of failed simple limbal epithelial transplantation (SLET): a case report.International journal of surgery case reports · 2026Article
- Ocular Surface Inflammation as a Driver of Cornea Limbal Stem Cell Deficiency: Mechanisms and Implications.International journal of molecular sciences · 2026Review
- Article
- Surface modified electrospun scaffold supports iPSC-derived limbal stem cell function.npj biomedical innovations · 2026Article
- Losartan Alleviates Chemical Burn-Induced Limbal Stem Cell Deficiency: Repurposing a Venerable Anti-Hypertension Drug.Investigative ophthalmology & visual science · 2026Article
- Limbal stem cell deficiency secondary to topical glaucoma medication: a scoping review.International journal of ophthalmology · 2026Review
- Subconjunctival Injection of Mesenchymal Stem Cells for Corneal Wound Healing After Chemical Injury: Impact on Epithelial Coverage, Limbal Ischemia, and Ocular Surface Inflammatory.Frontiers in medicine · 2026Article
- Recent Advances in Stem Cells of Corneal Epithelia.Investigative ophthalmology & visual science · 2025Review
- Combined Multilayered Amniotic Membrane Graft and Fibrin Glue as a Surgical Management of Limbal Dermoid Cyst.Journal of clinical medicine · 2025Article
- Combined Therapy Using Mesenchymal Stem Cells and Metal Nanoparticles: Perspectives for Ocular Injuries and Diseases.International journal of nanomedicine · 2025Review
- Analysis of Risk Factors of Postoperative Dry Eye in Cataract Patients Based on Lens Nucleus Hardness Grading.Risk management and healthcare policy · 2025Article
- Outcomes of Collagen Crosslinking in Patients with Keratoconus and Co-Existent Limbal Stem Cell Deficiency.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- In vivo Confocal Microscopy for Corneal and Ocular Surface Pathologies: A Comprehensive Review.Clinical ophthalmology (Auckland, N.Z.) · 2025Review
- Autologous simple limbal stem cell transplantation with conjunctival autograft in chronic unilateral total LSCD with severe symblepharon due to severe alkali burn.BMJ case reports · 2024Article
- Development of Biomimetic Substrates for Limbal Epithelial Stem Cells Using Collagen-Based Films, Hyaluronic Acid, Immortalized Cells, and Macromolecular Crowding.Life (Basel, Switzerland) · 2024Article
- Cellular structural and functional imaging of donor and pathological corneas with label-free dual-mode full-field optical coherence tomography.Biomedical optics express · 2024Article
- Beyond Vision: An Overview of Regenerative Medicine and Its Current Applications in Ophthalmological Care.Cells · 2024Review
- Prevalence of limbal stem cell deficiency at an academic referral center over a two-year period.Frontiers in ophthalmology · 2024Article
- Managing ocular allergy.Community eye health · 2024Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Limbal stem cell deficiency (LSCD) can cause significant corneal vascularization and scarring and often results in serious visual morbidity. An early and accurate diagnosis can help prevent the same with a timely and appropriate intervention. This review aims to provide an understanding of the different diagnostic tools and presents an algorithmic approach to the management based on a comprehensive clinical examination. Although the diagnosis of LSCD usually relies on the clinical findings, they can be subjective and non-specific. In such cases, using an investigative modality offers an objective method of confirming the diagnosis. Several diagnostic tools have been described in literature, each having its own advantages and limitations. Impression cytology and
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.