Evidence map›Paper›PMID 35692472›Full record

ArticleJournal of parasitic diseases : official organ of the Indian Society for Parasitology2022

The potentials of

Aswin Mohan, Shanitha Shaji, Sunitha Padmanabhan, Shahanas Naisam, Nidhin Sreekumar

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of parasitic diseases : official organ of the Indian Society for Parasitology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Aswin MohanDept. of Computational Biology and Bioinformatics, Kariavattom Campus, University of Kerala, Trivandrum, Kerala India.
Shanitha ShajiDept. of Computational Biology and Bioinformatics, Kariavattom Campus, University of Kerala, Trivandrum, Kerala India.
Sunitha PadmanabhanDept. of Computational Biology and Bioinformatics, Kariavattom Campus, University of Kerala, Trivandrum, Kerala India.
Shahanas NaisamAccubits Invent Pvt. Ltd, The Pirates Square, Trivandrum, Kerala India.
Nidhin SreekumarAccubits Invent Pvt. Ltd, The Pirates Square, Trivandrum, Kerala India.ORCID 0000-0001-9345-4471
University of Kerala · INAPJ Abdul Kalam Technological University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lymphatic filariasis is one of the major diseases that belong to the category of neglected tropical illness. Filarial nematodes are the cause of the disease and are transmitted to humans via blood-feeding arthropod vectors. Drugs such as Albendazole, Ivermectin and diethylcarbamazine are administered either individually or in combination to overcome the progress of the lymphatic filariasis. These drugs have some minor side effects like temporary hair loss, dizziness, nausea etc. The filarial parasites have multifunctional proteins including the Glutathione-s-transferase (GST) enzyme. This study aims at the identification of a natural molecule that has the potential to bind with the GST enzyme, which plays a major role in detoxification of endogenous electrophilic compounds. Thus the binding interrupts the detoxification process within the filarial parasite,

Indexed as

Brugia malayiCalotropis proceraLymphatic filariasisMolecular dockingMolecular dynamics

Identifiers

PMID35692472
PMCPMC9177934
OpenAlexW4241906145

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.