Evidence map›Paper›PMID 35692373›Full record

ArticleCardiovascular therapeutics2022

MIR22HG Aggravates Oxygen-Glucose Deprivation and Reoxygenation-Induced Cardiomyocyte Injury through the miR-9-3p/SH2B3 Axis.

Yi Ge, Lishi Liu, Liang Luo, Yu Fang, Tong Ni

Open access · goldAbstract read
In one paragraph

Article in Cardiovascular therapeutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yi GeDepartment of Intensive Care Unit, Wuxi Second People's Hospital, Wuxi, 214000 Jiangsu, China.
Lishi LiuDepartment of Intensive Care Unit, Wuxi Second People's Hospital, Wuxi, 214000 Jiangsu, China.ORCID https://orcid.org/0000-0001-5474-2139
Liang LuoDepartment of Intensive Care Unit, Wuxi Second People's Hospital, Wuxi, 214000 Jiangsu, China.
Yu FangDepartment of Intensive Care Unit, Wuxi Second People's Hospital, Wuxi, 214000 Jiangsu, China.
Tong NiDepartment of Intensive Care Unit, Wuxi Second People's Hospital, Wuxi, 214000 Jiangsu, China.
Xian Yang Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reperfusion therapy, the standard treatment for acute myocardial infarction (MI), can trigger necrotic death of cardiomyocytes and provoke ischemia/reperfusion (I/R) injury. However, molecular mechanisms that regulate cardiomyocyte death remain largely unknown. The abnormal expression of lncRNA MIR22HG has been found in types of diseases. The current study was aimed at exploring the function and mechanism of MIR22HG in I/R injury. In this study, mouse myocardial cells (HL-1) treated with oxygen-glucose deprivation and reoxygenation (OGD/R) were used as the

Indexed as

MicroRNAsMyocardial InfarctionMyocardial Reperfusion InjuryAnimalsApoptosisGlucoseMaleMiceMice, Inbred C57BLMyocytes, CardiacOxygenGlucoseMicroRNAsMIRN9 microRNA, mouseOxygen

Identifiers

PMID35692373
PMCPMC9173999
OpenAlexW4281783207

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.