Evidence map›Paper›PMID 35692303›Full record

ArticleGastroenterology report2022

Lymphocyte-to-monocyte ratio is a short-term predictive marker of ulcerative colitis after induction of advanced therapy.

Natsuki Ishida, Yusuke Asai, Takahiro Miyazu, Satoshi Tamura, Shinya Tani, Mihoko Yamade, Moriya Iwaizumi, Yasushi Hamaya, Satoshi Osawa, Takahisa Furuta and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Gastroenterology report, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Natsuki IshidaFirst Department of Medicine, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.
Yusuke AsaiFirst Department of Medicine, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.
Takahiro MiyazuFirst Department of Medicine, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.
Satoshi TamuraFirst Department of Medicine, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.
Shinya TaniDepartment of Endoscopic and Photodynamic Medicine, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.
Mihoko YamadeFirst Department of Medicine, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.
Moriya IwaizumiDepartment of Laboratory Medicine, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.
Yasushi HamayaFirst Department of Medicine, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.
Satoshi OsawaDepartment of Endoscopic and Photodynamic Medicine, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.
Takahisa FurutaCenter for Clinical Research, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.
Ken SugimotoFirst Department of Medicine, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.ORCID https://orcid.org/0000-0001-9586-1097
Hamamatsu University School of Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advanced therapies for patients with mild-to-severe ulcerative colitis (UC) may result in treatment failure. We examined whether the lymphocyte-to-monocyte ratio (L/M ratio) could predict the failure of advanced therapies. This retrospective, observational, cohort study included 73 patients who were treated with advanced therapies at the Hamamatsu University School of Medicine (Shizuoka, Japan) between February 2011 and November 2020. The patients were divided into the non-failure and failure groups, and their leukocyte counts and ratios before induction were examined. Univariate and multivariate analyses were performed to identify the prognostic factors. Advanced therapies failed within 3 months in 15 (20.5%) patients. Only the L/M ratio was significantly lower in the failure group than in the non-failure group (

Indexed as

advanced therapyfailurelymphocyte-to-monocyte ratioulcerative colitis

Identifiers

PMID35692303
PMCPMC9178621
OpenAlexW4285227993

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.