Evidence map›Paper›PMID 35692059›Full record

ArticleAllergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology2022

Patient selection for milk and egg ladders using a food ladder safety checklist.

Gilbert T Chua, Edmond S Chan, Joanne Yeung, Scott B Cameron, Lianne Soller, Brock A Williams, Alanna Chomyn, Timothy K Vander Leek, Elissa M Abrams, Raymond Mak and 1 more

Open access · goldAbstract readLetter
In one paragraph

Article in Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Eating away at food allergy.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
    Review
  5. Food oral immunotherapy.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Safety and effectiveness of the Canadian food ladders for children with IgE-mediated food allergies to cow's milk and/or egg.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2023
    Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Gilbert T ChuaDepartment of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 1/F, New Clinical Building, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong,, SAR, China. cgt560@hku.hk.ORCID http://orcid.org/0000-0003-0333-0059
Edmond S ChanDivision of Allergy and Immunology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.
Joanne YeungDivision of Allergy and Immunology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.
Scott B CameronDivision of Allergy and Immunology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.
Lianne SollerDivision of Allergy and Immunology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.
Brock A WilliamsDivision of Allergy and Immunology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.
Alanna ChomynDivision of Allergy and Immunology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.
Timothy K Vander LeekDepartment of Pediatrics, Pediatric Allergy & Asthma, University of Alberta, Edmonton, AB, Canada.
Elissa M AbramsDivision of Allergy and Immunology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.
Raymond MakDivision of Allergy and Immunology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.
Tiffany WongDivision of Allergy and Immunology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.
University of British Columbia · CAQueen Mary Hospital · CNUniversity of Alberta · CA

Funding

University of Hong Kong Project code: 202009185024
6 · The paper itself

Abstract

A food ladder is a form of home-based dietary advancement therapy that gradually increases exposure to an allergenic food through the gradual introduction of egg or milk containing food with increasing quantity and allergenicity from extensively heated forms, such as baked goods, to less processed products. While widely considered safe, the food ladder is not risk-free and most of the egg and milk ladder studies only included preschoolers with mild egg and milk allergies, and with no or well-controlled asthma. We propose a Food Ladder Safety Checklist to assist with patient selection using "4 A's" based on available evidence for food ladders, including Age, active or poorly controlled Asthma, history of Anaphylaxis, and Adherence.

Indexed as

Egg allergyFood laddersMilk allergySafety

Identifiers

PMID35692059
PMCPMC9188637
OpenAlexW4282043132

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.