ReviewJournal of obesity & metabolic syndrome2022
Regulation of Adipose Tissue Biology by Long-Chain Fatty Acids: Metabolic Effects and Molecular Mechanisms.
Review in Journal of obesity & metabolic syndrome, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 22 citations in OpenAlex.
- Short-, medium-, versus long-chain fatty acids: mechanisms of immunomodulation and disease pathogenesis.Cellular & molecular immunology · 2026Review
- Proteomic and Super-Resolution Analyses of Murine Brown Adipocyte-Derived Extracellular Vesicles.Journal of extracellular biology · 2026Article
- Consumption of Terminalia catappa powder: modulation of lipid metabolism, reduction of cardiovascular risk, and hepatic protection in aged Wistar rats.Biogerontology · 2026Article
- Plasma Fatty Acid Profiles Modulate PPARγ Expression in Adipose Tissue: A Lipidomic Insight Into Obesity-Related Metabolic Dysregulation.Endocrinology, diabetes & metabolism · 2025Article
- Near-infrared fatty acid molecular probe for image-guided surgery of glioblastoma.Npj imaging · 2025Article
- Article
- The global burden and biomarkers of cardiovascular disease attributable to ambient particulate matter pollution.Journal of translational medicine · 2025Article
- Identification of genomic regions associated with fatty acid metabolism across blood, liver, backfat and muscle in pigs.Genetics, selection, evolution : GSE · 2024Article
- Rabbit Meat Extract Induces Browning in 3T3-L1 Adipocytes via the AMP-Activated Protein Kinase Pathway.Foods (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
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Abstract
Long-chain fatty acids (LCFA) modulate metabolic, oxidative, and inflammatory responses, and the physiological effects of LCFA are determined by chain length and the degree of saturation. Adipose tissues comprise multiple cell types, and play a significant role in energy storage and expenditure. Fatty acid uptake and oxidation are the pathways through which fatty acids participate in the regulation of energy homeostasis, and their dysregulation can lead to the development of obesity and chronic obesity-related disorders, including type 2 diabetes, cardiovascular diseases, and certain types of cancer. Numerous studies have reported that many aspects of adipose tissue biology are influenced by the number and position of double bonds in LCFA, and these effects are mediated by various signaling pathways, including those regulating adipocyte differentiation (adipogenesis), thermogenesis, and inflammation in adipose tissue. This review aims to describe the underlying molecular mechanisms by which different types of LCFA influence adipose tissue metabolism, and to further clarify their relevance to metabolic dysregulation associated with obesity. A better understanding of the effects of LCFA on adipose tissue metabolism may lead to improved nutraceutical strategies to address obesity and obesity-associated diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.