Evidence map›Paper›PMID 35690875›Full record

ArticleBMC research notes2022

Challenges and solutions to recruitment of neonates and children having cardiac surgery into a study using a novel sampling device.

Terrie Walker-Smith, Daniel Fudulu, Aravind Ramesh, Karen Sheehan, Julie Madden, Lucy Culliford, Jonathan Evans, Gianni D Angelini, Thomas Upton, Ben Gibbison

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in BMC research notes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. The dynamic adrenal response of children to cardiac surgery and cardiac catheterization.The Journal of clinical endocrinology and metabolism · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Terrie Walker-SmithBristol Trials Centre, University of Bristol, Bristol, UK.
Daniel FuduluBristol Heart Institute, University of Bristol, Bristol, UK.
Aravind RameshBristol Heart Institute, University of Bristol, Bristol, UK.
Karen SheehanUniversity Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.
Julie MaddenUniversity Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.
Lucy CullifordBristol Trials Centre, University of Bristol, Bristol, UK.
Jonathan EvansBristol Trials Centre, University of Bristol, Bristol, UK.
Gianni D AngeliniBristol Heart Institute, University of Bristol, Bristol, UK.
Thomas UptonUniversity Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK.
Ben GibbisonBristol Heart Institute, University of Bristol, Bristol, UK. ben.gibbison@bristol.ac.uk.ORCID http://orcid.org/0000-0003-3635-6212
University Hospitals Bristol NHS Foundation Trust · GBUniversity of Bristol · GB

Funding

British Heart Foundation CH/1992027/7163British Heart Foundation PG/11/19/28827British Heart Foundation PG/13/9/29990British Heart Foundation PG/14/72/31080British Heart Foundation PG/15/95/31853Medical Research Council MR/J015350/1National Institute for Health Research Bristol BRC
6 · The paper itself

Abstract

objectiveTo narratively describe the challenges and solutions required in delivering a non-commercial study of children undergoing cardiac surgery using a novel subcutaneous hormone collection device.

resultsThe challenges faced by the research team are divided into those of conducting healthcare research in children and those specific to this study. Many of the issues of conducting healthcare research in children can and have been overcome by structural and institutional culture change-normalising and embedding research as part of good clinical care. The issues specific to insertion and maintenance of the novel collection device can be overcome by education and support of the clinical teams. The increased incentives and resources of commercial research may have overcome many of these.

Indexed as

Cardiac Surgical ProceduresChildHumansInfant, NewbornAdrenalCardiac surgeryHypothalamic-pituitary-adrenal axisPaediatric endocrinology

Identifiers

PMID35690875
PMCPMC9188008
OpenAlexW4282926959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.