Evidence map›Paper›PMID 35690691›Full record

ReviewJournal of perinatology : official journal of the California Perinatal Association2022

Hemodynamic consequences of respiratory interventions in preterm infants.

Arvind Sehgal, J Lauren Ruoss, Amy H Stanford, Satyan Lakshminrusimha, Patrick J McNamara

Erratum issuedOpen access · hybridAbstract readReview
In one paragraph

Review in Journal of perinatology : official journal of the California Perinatal Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Threshold to initiate chest compressions for bradycardia at birth: A narrative review.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Pooled it
  2. Trial
  3. Article
  4. Surfactant replacement therapy in preterm infants with congenital heart disease: Physiological concepts and therapeutic considerations.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Review
  5. Article
  6. Gestational age-specific effects of antenatal corticosteroids on early physiologic vulnerability and neonatal outcomes.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  7. Review
  8. Observational
  9. Article
  10. A non-invasive diagnostic tool for the assessment of optimal positive-end expiratory pressure (PEEPJournal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  11. Article
  12. Article
  13. Integration of inferior vena cava measurements into routine functional echocardiography in preterm neonates. Are We There Yet?Journal of perinatology : official journal of the California Perinatal Association · 2025
    Observational
  14. Article
  15. Review
  16. Review
  17. Article
  18. Ductus Arteriosus in Fetal and Perinatal Life.Journal of cardiovascular development and disease · 2024
    Review
  19. Review
  20. The association between patterns of early respiratory disease and diastolic dysfunction in preterm infants.Journal of perinatology : official journal of the California Perinatal Association · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Arvind SehgalMonash Newborn, Monash Children's Hospital, Melbourne, VIC, Australia. Arvind.Sehgal@monash.edu.ORCID http://orcid.org/0000-0003-2600-7529
J Lauren RuossUniversity of Florida, Department of Pediatrics, Gainesville, FL, USA.ORCID http://orcid.org/0000-0002-7714-565X
Amy H StanfordDivision of Neonatology, Department of Pediatrics and Internal Medicine, University of Iowa, Iowa City, LW, USA.
Satyan LakshminrusimhaDepartment of Pediatrics, UC Davis Children's Hospital, Sacramento, CA, USA.ORCID http://orcid.org/0000-0001-6098-2155
Patrick J McNamaraDivision of Neonatology, Department of Pediatrics and Internal Medicine, University of Iowa, Iowa City, LW, USA.ORCID http://orcid.org/0000-0001-7648-8872
University of Iowa · USMonash Children’s Hospital · AUUC Davis Children's Hospital · USUniversity of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advances in perinatal management have led to improvements in survival rates for premature infants. It is known that the transitional period soon after birth, and the subsequent weeks, remain periods of rapid circulatory changes. Preterm infants, especially those born at the limits of viability, are susceptible to hemodynamic effects of routine respiratory care practices. In particular, the immature myocardium and cardiovascular system is developmentally vulnerable. Standard of care (but essential) respiratory interventions, administered as part of neonatal care, may negatively impact heart function and/or pulmonary or systemic hemodynamics. The available evidence regarding the hemodynamic impact of these respiratory practices is not well elucidated. Enhanced diagnostic precision and therapeutic judiciousness are warranted. In this narrative, we outline (1) the vulnerability of preterm infants to hemodynamic disturbances (2) the hemodynamic effects of common respiratory practices; including positive pressure ventilation and surfactant therapy, and (3) identify tools to assess cardiopulmonary interactions and guide management.

Indexed as

Infant, Premature, DiseasesPulmonary SurfactantsRespiratory Distress Syndrome, NewbornHemodynamicsHumansInfantInfant, NewbornInfant, PrematureIntermittent Positive-Pressure VentilationPulmonary Surfactants

Identifiers

PMID35690691
PMCPMC9436777
OpenAlexW4282919276

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.