Evidence map›Paper›PMID 35690610›Full record

ArticleCell death discovery2022

Caspase-2 is a mediator of apoptotic signaling in response to gemtuzumab ozogamicin in acute myeloid leukemia.

Petra Hååg, Magnus Olsson, Jeremy Forsberg, Marita Lagergren Lindberg, Bo Stenerlöw, Dali Zong, Lena Kanter, Rolf Lewensohn, Kristina Viktorsson, Boris Zhivotovsky and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cell death discovery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 4 countries.

Petra HåågDepartment of Oncology-Pathology, Karolinska Institutet, SE-171 64, Solna, Sweden. Petra.Haag@ki.se.ORCID http://orcid.org/0000-0002-7045-867X
Magnus OlssonInstitute of Environmental Medicine, Karolinska Institutet, SE-171 77, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-6370-8423
Jeremy ForsbergInstitute of Environmental Medicine, Karolinska Institutet, SE-171 77, Stockholm, Sweden.
Marita Lagergren LindbergDepartment of Oncology-Pathology, Karolinska Institutet, SE-171 64, Solna, Sweden.
Bo StenerlöwDepartment of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, SE-75185, Uppsala, Sweden.ORCID http://orcid.org/0000-0001-8878-8071
Dali ZongDepartment of Oncology-Pathology, Karolinska Institutet, SE-171 64, Solna, Sweden.ORCID http://orcid.org/0000-0001-6019-2970
Lena KanterDepartment of Oncology-Pathology, Karolinska Institutet, SE-171 64, Solna, Sweden.
Rolf LewensohnDepartment of Oncology-Pathology, Karolinska Institutet, SE-171 64, Solna, Sweden.
Kristina ViktorssonDepartment of Oncology-Pathology, Karolinska Institutet, SE-171 64, Solna, Sweden.ORCID http://orcid.org/0000-0003-4552-3561
Boris ZhivotovskyInstitute of Environmental Medicine, Karolinska Institutet, SE-171 77, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-2238-3482
Leif StenkeDepartment of Oncology-Pathology, Karolinska Institutet, SE-171 64, Solna, Sweden.
Karolinska Institutet · SEKarolinska University Hospital · SELomonosov Moscow State University · RUUppsala University · SE

Funding

Cancerfonden (Swedish Cancer Society) #190345Cancerfonden (Swedish Cancer Society) CAN 2015/401Cancerfonden (Swedish Cancer Society) CAN 2016/649Cancerfonden (Swedish Cancer Society) CAN 2018/597Cancerfonden (Swedish Cancer Society) CAN 2019/221Cancerfonden (Swedish Cancer Society) CAN 2021/1469 Pj01 HCancerföreningen i Stockholm (Cancer Society in Stockholm) #151122Cancerföreningen i Stockholm (Cancer Society in Stockholm) #171123Cancerföreningen i Stockholm (Cancer Society in Stockholm) #181301Cancerföreningen i Stockholm (Cancer Society in Stockholm) #191293Cancerföreningen i Stockholm (Cancer Society in Stockholm) #201202Familjen Erling-Perssons Stiftelse (Erling-Persson Family Foundation) # 2-2792/2017Familjen Erling-Perssons Stiftelse (Erling-Persson Family Foundation) # 4-1989/2020Ministry of Health and Social Affairs | Socialstyrelsen (National Board of Health and Welfare) # 2-2088/2017Ministry of Health and Social Affairs | Socialstyrelsen (National Board of Health and Welfare) #2-2088/2017Stockholms Läns Landsting (Stockholm County Council) # 20180404
6 · The paper itself

Abstract

The antibody conjugate gemtuzumab ozogamicin (GO; Mylotarg

Identifiers

PMID35690610
PMCPMC9188552
OpenAlexW4282938802

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.