ArticleThe Journal of emergency medicine2022
A Case of Leukocytoclastic Vasculitis Following SARS-COV-2 Vaccination.
Article in The Journal of emergency medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- Coronavirus disease 2019, vaccination against coronavirus and immunoglobulin A-mediated diseases: systematic literature review.Journal of autoimmunity · 2022Pooled it
- Tigecycline Induced Hemorrhagic Vesiculobullous Leukocytoclastic Vasculitis: A Rare Clinical Presentation.Oman medical journal · 2026Article
- Cutaneous small vessel vasculitis in the COVID-19 era: a systematic review.Skin health and disease · 2025Review
- Onset of leukocytoclastic vasculitis following covid-19 vaccination: case based comprehensive review.Rheumatology international · 2024Review
- COVID-19 vaccine-associated vasculitis: A systematic review.SAGE open medicine · 2024Review
- New-Onset Rheumatic Immune-Mediated Inflammatory Diseases Following SARS-CoV-2 Vaccinations until May 2023: A Systematic Review.Vaccines · 2023Review
- Leukocytoclastic Vasculitis and SARS-COV-2 Vaccination.The Journal of emergency medicine · 2022Article
- SARS-CoV-2 vaccination-induced cutaneous vasculitis: Report of two new cases and literature review.Dermatologic therapy · 2022Review
- Cutaneous vasculitis and vasculopathy in the era of COVID-19 pandemic.Frontiers in medicine · 2022Review
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough vaccination against coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been proven generally safe, rare but potentially serious adverse reactions do occur. Leukocytoclastic vasculitis (LCV) is a small-vessel vasculitis that has been associated with other immunizations, but, to our knowledge, has not been previously reported in association with vaccines directed against SARS-CoV-2. CASE REPORT: We report the case of a 22-year-old man with no known past medical history who presented to the Emergency Department with 2 days of migratory arthritis in his ankles and palpable purpura on his bilateral lower extremities, occurring 10 days after receiving the Johnson & Johnson SARS-CoV-2 vaccine. The patient's clinical presentation was suggestive of leukocytoclastic vasculitis, and this diagnosis was confirmed on skin biopsy. Why Should an Emergency Physician Be Aware of This? Recognition of vasculitides is important for timely treatment and prevention of complications. In a patient presenting with palpable purpura after immunization against SARS-CoV-2, LCV should be promptly considered and worked up by the Emergency Physician, though management is most often entirely outpatient and the clinical course is typically mild and self-resolving.
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Registered trials
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