Evidence map›Paper›PMID 35690495›Full record

ReviewBiological psychiatry2022

Functional Connectome-Based Predictive Modeling in Autism.

Corey Horien, Dorothea L Floris, Abigail S Greene, Stephanie Noble, Max Rolison, Link Tejavibulya, David O'Connor, James C McPartland, Dustin Scheinost, Katarzyna Chawarska and 2 more

Abstract readReview
In one paragraph

Review in Biological psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

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  16. Review
  17. Brain-based graph-theoretical predictive modeling to map the trajectory of anhedonia, impulsivity, and hypomania from the human functional connectome.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Article
  18. Article
  19. Article
  20. Connectome-based predictive modeling of Internet addiction symptomatology.Social cognitive and affective neuroscience · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Corey HorienInterdepartmental Neuroscience Program, Yale School of Medicine, New Haven, Connecticut; MD-PhD Program, Yale School of Medicine, New Haven, Connecticut. Electronic address: corey.horien@yale.edu.
Dorothea L FlorisMethods of Plasticity Research, Department of Psychology, University of Zürich, Zurich, Switzerland; Donders Center for Brain, Cognition and Behavior, Radboud University Nijmegen, Nijmegen, The Netherlands.
Abigail S GreeneInterdepartmental Neuroscience Program, Yale School of Medicine, New Haven, Connecticut; MD-PhD Program, Yale School of Medicine, New Haven, Connecticut.
Stephanie NobleDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut.
Max RolisonYale Child Study Center, New Haven, Connecticut.
Link TejavibulyaInterdepartmental Neuroscience Program, Yale School of Medicine, New Haven, Connecticut.
David O'ConnorDepartment of Biomedical Engineering, Yale University, New Haven, Connecticut.
James C McPartlandDepartment of Psychology, Yale University, New Haven, Connecticut; Yale Child Study Center, New Haven, Connecticut.
Dustin ScheinostInterdepartmental Neuroscience Program, Yale School of Medicine, New Haven, Connecticut; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut; Department of Biomedical Engineering, Yale University, New Haven, Connecticut; Department of Statistics and Data Science, Yale University, New Haven, Connecticut; Yale Child Study Center, New Haven, Connecticut.
Katarzyna ChawarskaDepartment of Pediatrics, Yale School of Medicine, New Haven, Connecticut; Department of Statistics and Data Science, Yale University, New Haven, Connecticut; Yale Child Study Center, New Haven, Connecticut.
Evelyn M R LakeDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut.
R Todd ConstableInterdepartmental Neuroscience Program, Yale School of Medicine, New Haven, Connecticut; Department of Neurosurgery, Yale School of Medicine, New Haven, Connecticut; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut; Department of Biomedical Engineering, Yale University, New Haven, Connecticut. Electronic address: todd.constable@yale.edu.

Funding

The Autism Biomarkers Consortium for Clinical TrialsU19MH108206 · NIMH · YALE UNIVERSITY · PI MCPARTLAND, JAMES CHARLES · 2015 to 2024
$68.8M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007205 · NIGMS · YALE UNIVERSITY · PI KAZMIERCZAK, BARBARA I · 1985 to 2019
$42.9M
Statistical Analysis CoreP50MH115716 · NIMH · YALE UNIVERSITY · PI CHAWARSKA, KATARZYNA · 2017 to 2021
$11.5M
NRSA Training CoreTL1TR001864 · NCATS · YALE UNIVERSITY · PI CANTLEY, LLOYD G, EDELMAN, E. JENNIFER · 2016 to 2025
$9.9M
Development of Face Processing in Infants with Autism Spectrum DisordersR01MH087554 · NIMH · YALE UNIVERSITY · PI CHAWARSKA, KATARZYNA · 2010 to 2014
$2.0M
Adapting Biomarker Assays for Individuals with Autism and Intellectual DisabilityR21MH122202 · NIMH · YALE UNIVERSITY · PI MCPARTLAND, JAMES CHARLES, NAPLES, ADAM JOHN · 2019 to 2020
$461k
NCATS NIH HHS TL1 TR001864NIGMS NIH HHS T32 GM007205NIMH NIH HHS P50 MH115716NIMH NIH HHS R01 MH087554NIMH NIH HHS R21 MH122202NIMH NIH HHS U19 MH108206
6 · The paper itself

Abstract

Autism is a heterogeneous neurodevelopmental condition, and functional magnetic resonance imaging-based studies have helped advance our understanding of its effects on brain network activity. We review how predictive modeling, using measures of functional connectivity and symptoms, has helped reveal key insights into this condition. We discuss how different prediction frameworks can further our understanding of the brain-based features that underlie complex autism symptomatology and consider how predictive models may be used in clinical settings. Throughout, we highlight aspects of study interpretation, such as data decay and sampling biases, that require consideration within the context of this condition. We close by suggesting exciting future directions for predictive modeling in autism.

Indexed as

Autism Spectrum DisorderAutistic DisorderConnectomeBrainForecastingHumansMagnetic Resonance ImagingClinical translationDevelopmentFingerprintingIndividual differencesMachine learningResting-state fMRI

Identifiers

PMID35690495
PMCPMC10948028

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.