Evidence map›Paper›PMID 35690489›Full record

ArticleBritish journal of anaesthesia2022

Association between intraoperative tidal volume and postoperative respiratory complications is dependent on respiratory elastance: a retrospective, multicentre cohort study.

Aiman Suleiman, Eduardo Costa, Peter Santer, Tim M Tartler, Luca J Wachtendorf, Bijan Teja, Guanqing Chen, Elias Baedorf-Kassis, Alexander Nagrebetsky, Marcos F Vidal Melo and 2 more

Abstract readMulticenter Study
In one paragraph

Article in British journal of anaesthesia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Aiman SuleimanDepartment of Anaesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Centre, Boston, MA, USA; Center for Anaesthesia Research Excellence (CARE), Beth Israel Deaconess Medical Centre, Boston, MA, USA; Department of Anaesthesia and Intensive Care, Faculty of Medicine, University of Jordan, Amman, Jordan.
Eduardo CostaLaboratório de Pneumologia LIM-09, Disciplina de Pneumologia, Heart Institute (Incor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil; Research and Education Institute, Hospital Sírio-Libanes, Sao Paulo, Brazil.
Peter SanterDepartment of Anaesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Centre, Boston, MA, USA.
Tim M TartlerDepartment of Anaesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Centre, Boston, MA, USA; Center for Anaesthesia Research Excellence (CARE), Beth Israel Deaconess Medical Centre, Boston, MA, USA.
Luca J WachtendorfDepartment of Anaesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Centre, Boston, MA, USA; Center for Anaesthesia Research Excellence (CARE), Beth Israel Deaconess Medical Centre, Boston, MA, USA; Department of Anaesthesiology, Montefiore Medical Centre and Albert Einstein College of Medicine, Bronx, NY, USA.
Bijan TejaDepartment of Anaesthesiology and Pain Medicine and Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada.
Guanqing ChenCenter for Anaesthesia Research Excellence (CARE), Beth Israel Deaconess Medical Centre, Boston, MA, USA.
Elias Baedorf-KassisDepartment of Pulmonary, Critical Care & Sleep Medicine, Beth Israel Deaconess Medical Centre, Boston, MA, USA.
Alexander NagrebetskyDepartment of Anaesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA, USA.
Marcos F Vidal MeloDepartment of Anesthesiology, Columbia University Irving Medical Center, New York, NY, USA. Electronic address: mv2869@cumc.columbia.edu.
Matthias EikermannDepartment of Anaesthesiology, Montefiore Medical Centre and Albert Einstein College of Medicine, Bronx, NY, USA; Klinik für Anästhesiologie und Intensivmedizin, Universität Duisburg-Essen, Essen, Germany.
Maximilian S SchaeferDepartment of Anaesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Centre, Boston, MA, USA; Center for Anaesthesia Research Excellence (CARE), Beth Israel Deaconess Medical Centre, Boston, MA, USA; Department of Anaesthesiology, Düsseldorf University Hospital, Dusseldorf, Germany. Electronic address: msschaef@bidmc.harvard.edu.

Funding

Research Training for AnesthetistsT32GM007592 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI STUART A FORMAN · 1985 to 2026
$11.8M
1/2: An Anesthesia-Centered Bundle to Reduce Postoperative Pulmonary Complications: The PRIME-AIR StudyUH3HL140177 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI FERNANDEZ-BUSTAMANTE, ANA, VIDAL MELO, MARCOS F · 2020 to 2023
$6.6M
Regional Tidal Lung Strain and Neutrophilic Inflammation in Early Lung InjuryR01HL121228 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI VIDAL MELO, MARCOS F · 2014 to 2023
$6.2M
NHLBI NIH HHS R01 HL121228NHLBI NIH HHS UH3 HL140177NIGMS NIH HHS T32 GM007592
6 · The paper itself

Abstract

backgroundThe impact of high vs low intraoperative tidal volumes on postoperative respiratory complications remains unclear. We hypothesised that the effect of intraoperative tidal volume on postoperative respiratory complications is dependent on respiratory system elastance.

methodsWe retrospectively recorded tidal volume (Vt; ml kg

resultsOverall, 10 821/197 474 (5.5%) patients sustained postoperative respiratory complications. Higher Vt was associated with greater risk of postoperative respiratory complications (adjusted odds ratio=1.42 per ml kg

conclusionsThe association of harm with higher tidal volumes during intraoperative mechanical ventilation is modified by respiratory system elastance. These data suggest that respiratory elastance should inform the design of perioperative trials testing intraoperative ventilatory strategies.

Indexed as

Positive-Pressure RespirationRespiration DisordersCohort StudiesHumansPostoperative ComplicationsRespiration, ArtificialRespiratory SystemRetrospective StudiesTidal Volumedriving pressurelung protective ventilationmechanical ventilationpostoperative pulmonary complicationsrespiratory system elastancetidal volume

Identifiers

PMID35690489
PMCPMC9837741

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.