Evidence map›Paper›PMID 35689897›Full record

ArticleEuropean journal of cancer (Oxford, England : 1990)2022

Linking EORTC QLQ-C-30 and PedsQL/PEDQOL physical functioning scores in patients with osteosarcoma.

Axel Budde, Katja Baust, Leonie Weinhold, Mark Bernstein, Stefan Bielack, Catharina Dhooge, Lars Hjorth, Katherine A Janeway, Meriel Jenney, Mark D Krailo and 9 more

Erratum issuedAbstract read
In one paragraph

Article in European journal of cancer (Oxford, England : 1990), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Evaluation of the MOVE online exercise programme for young people aged 13-30.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Axel BuddeDepartment of Paediatric Haematology and Oncology, University Hospital Bonn, Bonn, Germany. Electronic address: axel.budde@ukbonn.de.
Katja BaustDepartment of Paediatric Haematology and Oncology, University Hospital Bonn, Bonn, Germany.
Leonie WeinholdDepartment of Medical Biometry, Informatics, and Epidemiology, University Hospital Bonn, Bonn, Germany.
Mark BernsteinIWK Health Centre, Dalhousie University, Halifax, NS, Canada.
Stefan BielackZentrum für Kinder-, Jugend- und Frauenmedizin, Pädiatrie, Klinikum Stuttgart, Olgahospital, Stuttgart, Germany.
Catharina DhoogeDepartment of Internal Medicine and Paediatrics, Faculty of Medicine and Health Sciences, Ghent University Hospital, Ghent, Belgium.
Lars HjorthDepartment of Clinical Sciences, Department of Paediatrics, Lund University, Skane University Hospital, Lund, Sweden.
Katherine A JanewayDana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, MA, USA.
Meriel JenneyWomen's Services Clinical Board, University Hospital of Wales, Cardiff, UK.
Mark D KrailoStatistics and Data Center, Children's Oncology Group, Monrovia, CA, USA.
Neyssa MarinaFive Prime Therapeutics, South San Francisco, CA, USA.
Rajaram NagarajanDivision of Oncology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Sigbjørn SmelandNorwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.
Matthew R SydesMRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, University College London, London, UK.
Patricia De VosDepartment of Paediatric Haematology and Oncology, Ghent University Hospital, Ghent, Belgium.
Jeremy WhelanDepartment of Oncology, University College Hospital, London, UK.
Andreas WienerWest German Proton Therapy Center Essen, Essen, Germany.
Gabriele CalaminusDepartment of Paediatric Haematology and Oncology, University Hospital Bonn, Bonn, Germany.
Matthias SchmidDepartment of Medical Biometry, Informatics, and Epidemiology, University Hospital Bonn, Bonn, Germany.

Funding

NCTN BIQSFP ANBL1531 (NRT)U10CA180886 · NCI · PUBLIC HEALTH INSTITUTE · PI Douglas S. Hawkins · 2014 to 2026
$390.6M
COG SDMC - Statistics CoreU10CA180899 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TODD A ALONZO · 2014 to 2026
$132.8M
Medical Research Council MC_UU_00004/02Medical Research Council MC_UU_12023/28NCI NIH HHS U10 CA180886NCI NIH HHS U10 CA180899
6 · The paper itself

Abstract

purposeThe available questionnaires for quality-of-life (QoL) assessments are age-group specific, limiting comparability and impeding longitudinal analyses. The comparability of measurements, however, is a necessary condition for gaining scientific evidence. To overcome this problem, we assessed the viability of harmonising data from paediatric and adult patient-reported outcome (PRO) measures.

methodTo this end, we linked physical functioning scores from the Paediatric Quality of Life Inventory (PedsQL) and the Paediatric Quality of Life Questionnaire (PEDQOL) to the European Organisation for Research and Treatment of Cancer Core Questionnaire (EORTC QLQ-C30) for adults. Samples from the EURAMOS-1 QoL sub-study of 75 (PedsQL) and 112 (PEDQOL) adolescent osteosarcoma patients were concurrently administered both paediatric and adult questionnaires on 98 (PedsQL) and 156 (PEDQOL) occasions. We identified corresponding scores using the single-group equipercentile linking method.

resultsLinked physical functioning scores showed sufficient concordance to the EORTC QLQ-C30: Lin's ρ = 0.74 (PedsQL) and Lin's ρ = 0.64 (PEDQOL).

conclusionScore linking provides clinicians and researchers with a common metric for assessing QoL with PRO measures across the entire lifespan of patients.

Indexed as

Bone NeoplasmsOsteosarcomaAdolescentAdultChildFemaleHumansQuality of LifeSurveys and QuestionnairesChildhood cancerEORTC QLQ-C30Paediatric quality of life inventory (PedsQL)Paediatric quality of life questionnaire (PEDQOL)Patient-reported outcome (PRO)Physical functioning quality-of-life (QoL)Score linking

Identifiers

PMID35689897
PMCPMC9251607

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.