Evidence map›Paper›PMID 35689597›Full record

ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2022

Factors affecting obstructive sleep apnea patients' use of upper airway stimulation treatment.

Faith S Luyster, Quan Ni, Kent Lee, Christine Harrison, Vaibhav H Ramprasad, Ryan J Soose, Patrick J Strollo

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04768543 (Stimulation Therapy for Apnea), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04768543 completednot on this map

Stimulation Therapy for Apnea: Reporting Thoughts

TypeobservationalSponsorUniversity of PittsburghRan2020 to 2021Enrolled26ConditionsObstructive Sleep ApneaArmsUpper airway stimulation (Inspire Medical Systems, Inc.)
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Combination Tonsillectomy and Hypoglossal Nerve Stimulation for Sleep Apnea Patients With Oropharyngeal Lateral Wall Collapse.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2024
    Article
  2. Reduced usage of upper airway stimulation therapy in patients with comorbid insomnia and obstructive sleep apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Faith S LuysterSchool of Nursing, University of Pittsburgh, Pittsburgh, Pennsylvania.
Quan NiInspire Medical Systems, Inc., Minneapolis, Minnesota.
Kent LeeInspire Medical Systems, Inc., Minneapolis, Minnesota.
Christine HarrisonDepartment of Otolaryngology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Vaibhav H RamprasadDepartment of Otolaryngology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Ryan J SooseDepartment of Otolaryngology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Patrick J StrolloDepartment of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
University of Pittsburgh · USInspire Medical Systems (United States) · USIn-Q-Tel · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

objectivesUpper airway stimulation (UAS) is an alternative treatment for obstructive sleep apnea that must be activated nightly. Although the implanted device offsets the mask- or pressure-related side effects often associated with continuous positive airway pressure therapy, some UAS recipients do not use the therapy consistently. This study qualitatively explored factors associated with UAS usage in obstructive sleep apnea patients.

methodsSemistructured interviews were conducted with 24 obstructive sleep apnea patients who received UAS treatment. Twelve patients were categorized as high users with mean usage of ≥ 4 hours/night and 12 were categorized as low users with < 4 hours/night or nonuse. Interviews explored patients' experiences regarding barriers and facilitators to UAS use and their advice for new UAS recipients. Demographic and clinical data including the Insomnia Severity Index and Generalized Anxiety Disorder Scale were collected.

resultsCompared to high users, low users had higher levels of insomnia (mean Insomnia Severity Index: 3.6 vs 15.2, respectively) and anxiety (mean Generalized Anxiety Disorder Scale: 3.4 vs 6.9). High users reported more positive experiences with UAS treatment, such as improvements in symptoms and convenience of treatment, as facilitators of use. Low users tended to focus on the negative aspects of treatment, particularly stimulation-related discomfort and associated sleep disturbance.

conclusionsInsomnia with or without anxiety contributes to differing patient-reported experiences in high vs low user groups, with increased insomnia symptoms among low users. Improved understanding of the specific barrier and facilitators of UAS adherence may drive better long-term use and more personalized management strategies, including concomitant insomnia treatment. CLINICAL TRIALS REGISTRATION: Registry: ClinicalTrials.gov; Name: Stimulation Therapy for Apnea: Reporting Thoughts (START); URL: https://clinicaltrials.gov/ct2/show/NCT04768543; Identifier: NCT04768543. CITATION: Luyster FS, Ni Q, Lee K, et al. Factors affecting obstructive sleep apnea patients' use of upper airway stimulation treatment.

Indexed as

Electric Stimulation TherapySleep Apnea, ObstructiveSleep Initiation and Maintenance DisordersContinuous Positive Airway PressureHumansRegistriesTreatment Outcomeinsomniaobstructive sleep apneaqualitativetreatment adherenceupper airway stimulation

Identifiers

PMID35689597
PMCPMC9435328
OpenAlexW4282823200

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.