ArticleMicrobial biotechnology2022
High-throughput colorimetric assays optimized for detection of ketones and aldehydes produced by microbial cell factories.
Article in Microbial biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 13 citations in OpenAlex.
- Rational Design of an Electronically Gated Dicyano-BODIPY Platform for Reversible-Covalent Imaging of Methylglyoxal.JACS Au · 2026Article
- High-Throughput Screening of Industrial Brewing Yeast with Lower Synthetic Level of Acetaldehyde During Beer Production.Foods (Basel, Switzerland) · 2025Article
- Navigating Side Reactions for Robust Colorimetric Detection of Galactose Oxidase Activity.Analytical chemistry · 2025Article
- Leveraging EngineeredACS synthetic biology · 2025Article
- One-Pot Biosynthesis of Acetone from Waste Poly(hydroxybutyrate).ACS sustainable chemistry & engineering · 2024Article
- Article
- Synthetic metabolism forRSC chemical biology · 2022Article
- High-throughput colorimetric assays optimized for detection of ketones and aldehydes produced by microbial cell factories.Microbial biotechnology · 2022Article
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Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Randomized strain and pathway engineering are critical to improving microbial cell factory performance, calling for the development of high-throughput screening and selection systems. To facilitate this effort, we have developed two 96-well plate format colorimetric assays for reliable quantification of various ketones and aldehydes from culture supernatants, based on either a vanillin-acetone reaction or the 2,4-dinitrophenylhydrazine (2,4-DNPH) reagent. The vanillin-acetone assay enabled accurate and selective measurement of acetone titers up to 2 g l
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