Evidence map›Paper›PMID 35689234›Full record

ArticleBMC oral health2022

Prevalence, correlates and treatment needs of dental caries among people on antiretroviral therapy in Uganda: a cross sectional study.

Wilfred Arubaku, Godfrey Kwizera, Deusdedit Tusubira, Michael Kanyesigye, Steffany Chamut, Brittany Anne Seymour, Mark J Siedner, Vallence Niyonzima, Josephine N Najjuma, Samuel Maling

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Article in BMC oral health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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0cells of the map it votes in
5citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Wilfred ArubakuDepartment of Dental Surgery, Mbarara University of Science and Technology, Mbarara, Uganda.
Godfrey KwizeraDepartment of Dental Surgery, Mbarara University of Science and Technology, Mbarara, Uganda.
Deusdedit TusubiraDepartment of Biochemistry, Mbarara University of Science and Technology, Mbarara, Uganda.
Michael KanyesigyeMbarara Regional Referral Hospital, Mbarara, Uganda.
Steffany ChamutDepartment of Oral Health Policy and Epidemiology, Harvard School of Dental Medicine, Boston, USA.
Brittany Anne SeymourDepartment of Oral Health Policy and Epidemiology, Harvard School of Dental Medicine, Boston, USA.
Mark J SiednerDepartment of Medicine, Massachusetts General Hospital, Boston, USA.
Vallence NiyonzimaDepartment of Nursing, Mbarara University of Science and Technology, Mbarara, Uganda.
Josephine N NajjumaDepartment of Nursing, Mbarara University of Science and Technology, Mbarara, Uganda.
Samuel MalingDepartment of Psychiatry, Mbarara University of Science and Technology, P O Box 1410, Mbarara, Uganda. sammaling@must.ac.ug.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOral diseases are estimated to affect half of people living with HIV in the western world, and are often marked by pain, discomfort, disfigurement and reduced quality of life. Both HIV-specific and antiretroviral therapy-associated oral diseases have been found in this population. However, the prevalence, correlates and treatment needs of dental caries among people on antiretroviral therapy has not been well studied in rural Africa where majority of people living with HIV reside. Moreover, health behaviors and access to dental care vary significantly from high-income countries in the global north.

methodsA cross-sectional study was conducted among people living with HIV attending a high-volume HIV clinic with an enrollment of 10,000 patients in a regional referral hospital in Southwestern Uganda. The clinic is located in an urban setting with a large rural catchment area. Oral health data was collected using the modified World Health Organization oral health questionnaire for adults. Dental examinations were conducted to identify and classify dental caries using the decayed, missing, filled, teeth (DMFT) index and compute the treatment need. Logistic regression models were employed to identify correlate of dental caries.

resultsA total of 194 participants were included in the study. The majority were female (124/194, 63.9%) with a median age of 42 years (IQR 36-49). The prevalence of dental caries experience among study participants was 67%, (130/194, 95% CI 60-75%). The mean DMFT index score was 4 (IQR 2-6) and treatment need was 96% (192/200). A higher CD4 count was associated with the presence of dental caries (OR 0.403, 95% CI 0.175-0.932) although it was not significant in multivariate analysis.

conclusionThere is a high prevalence of dental caries among people living with HIV on ART in Uganda. Our data demonstrate a high oral treatment need among this population. We recommend inclusion of preventive and therapeutic oral care into HIV care in this region.

Indexed as

Dental CariesHIV InfectionsMouth DiseasesAdultCross-Sectional StudiesDMF IndexFemaleHumansMaleMiddle AgedOral HealthPrevalenceQuality of LifeUgandaAntiretroviral therapyDental cariesHIVOral diseases

Identifiers

PMID35689234
PMCPMC9188082

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.