Evidence map›Paper›PMID 35689210›Full record

ArticleBMC ophthalmology2022

Evaluation of a self-imaging SD-OCT system designed for remote home monitoring.

Judy E Kim, Oren Tomkins-Netzer, Michael J Elman, David R Lally, Michaella Goldstein, Dafna Goldenberg, Shiri Shulman, Gidi Benyamini, Anat Loewenstein

Registry-linked trialAbstract read
In one paragraph

Article in BMC ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06610747 (Home Care Monitoring of Visual Acuity and OCT Versus Standard Hospital/Clinic Care Monitoring During Diabetic Macular Edema Management), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06610747 narecruitingnot on this mapstarted 2024, after this paper: background citation

Home Care Monitoring of Visual Acuity and OCT Versus Standard Hospital/Clinic Care Monitoring During Diabetic Macular Edema Management: A Non-inferiority Randomized Clinical Trial

TypeinterventionalSponsorZhongshan Ophthalmic Center, Sun Yat-sen UniversityRan2024 to 2027Enrolled308ConditionsDiabetic Macular EdemaArmsHome-based Care Monitoring, Aflibercept 2Mg/0.05Ml Inj,Oph, Laser Treatment, Standard Hospital/clinic-based Care Monitoring
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Observational
  12. Article
  13. Analysis of OCT Scanning Parameters in AMD and RVO.Diagnostics (Basel, Switzerland) · 2024
    Article
  14. Article
  15. Review
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Judy E KimThe Eye Institute, Medical College of Wisconsin, 925 N. 87th street, Milwaukee, WI, 53226, USA. jekim@mcw.edu.
Oren Tomkins-NetzerDepartment of Ophthalmology, Lady Davis Carmel Medical Center, Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel.
Michael J ElmanElman Retina Group PA, Baltimore, MD, USA.
David R LallyRetina Research Institute at New England Retina Consultants, Springfield, MA, USA.
Michaella GoldsteinTel Aviv Medical Center, Tel Aviv, Israel.
Dafna GoldenbergAssuta Medical Centers, Tel Aviv, Israel.
Shiri ShulmanAssuta Medical Centers, Tel Aviv, Israel.
Gidi BenyaminiNotal Vision, Tel Aviv, Israel.
Anat LoewensteinTel Aviv Medical Center, Tel Aviv, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare identification rates of retinal fluid of the Notal Vision Home Optical Coherence Tomography (OCT) device (NVHO) when used by people with age-related macular degeneration (AMD) to those captured by a commercial OCT.

methodsProspective, cross-sectional study where patients underwent commercial OCT imaging followed by self-imaging with either the NVHO 2.5 or the NVHO 3 in clinic setting. Outcomes included patients' ability to acquire analyzable OCT images with the NVHO and to compare those with commercial images.

resultsSuccessful images were acquired with the NVHO 2.5 in 469/531 eyes (88%) in 264/290 subjects (91%) with the mean (SD) age of 78.8 (8.8); 153 (58%) were female with median visual acuity (VA) of 20/40. In the NVHO 3 cohort, 69 eyes of 45 subjects (93%) completed the self-imaging. Higher rates of successful imaging were found in eyes with VA ≥ 20/320. Positive percent agreement/negative percent agreement for detecting the presence of subretinal and/or intraretinal fluid when reviewing for fluid in three repeated volume scans were 97%/95%, respectively for the NVHO v3.

conclusionSelf-testing with the NVHO can produce high quality images suitable for fluid identification by human graders, suggesting the device may be able to complement standard-of-care clinical assessments and treatments.

Indexed as

Macular DegenerationTomography, Optical CoherenceCross-Sectional StudiesFemaleHumansMaleProspective StudiesVisual AcuityAge-related macular degenerationHome monitoringHOME OCT

Identifiers

PMID35689210
PMCPMC9186475

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.