Evidence map›Paper›PMID 35689161›Full record

ArticleAdvances in therapy2022

The Economic Burden of Eosinophilic Gastritis and Eosinophilic Enteritis in the United States.

Michael Woolley, Erin E Cook, Fan Mu, Keith A Betts, Emma Billmyer, Erica Yim, Jingyi Chen, Eric Q Wu

Open access · hybridAbstract read
In one paragraph

Article in Advances in therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Trends in the burden and quality of care for upper gastrointestinal diseases from 1990 to 2021: An analysis of the global burden of disease study 2021.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2026
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Michael WoolleyAllakos Inc., San Carlos, CA, USA.
Erin E CookAnalysis Group Inc., 111 Huntington Avenue, 14th Floor, Boston, MA, 02199, USA.
Fan MuAnalysis Group Inc., 111 Huntington Avenue, 14th Floor, Boston, MA, 02199, USA. Fan.Mu@analysisgroup.com.ORCID http://orcid.org/0000-0003-0252-0387
Keith A BettsAnalysis Group Inc., 111 Huntington Avenue, 14th Floor, Boston, MA, 02199, USA.
Emma BillmyerAnalysis Group Inc., 111 Huntington Avenue, 14th Floor, Boston, MA, 02199, USA.
Erica YimAnalysis Group Inc., 111 Huntington Avenue, 14th Floor, Boston, MA, 02199, USA.
Jingyi ChenAnalysis Group Inc., 111 Huntington Avenue, 14th Floor, Boston, MA, 02199, USA.
Eric Q WuAnalysis Group Inc., 111 Huntington Avenue, 14th Floor, Boston, MA, 02199, USA.
Analysis Group (United States) · USAllakos (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionEosinophilic gastritis and eosinophilic enteritis (EoG/EoN) are associated with a substantial clinical burden. However, limited information is available regarding the economic burden of EoG/EoN. This study was conducted to compare healthcare resource use (HRU) and costs among patients with EoG/EoN versus without EoG/EoN in the USA.

methodsAdministrative claims data from the IBM MarketScan

resultsA total of 2219 patients with EoG/EoN and 6657 patients without EoG/EoN were analyzed. Significantly higher proportions of patients with EoG/EoN versus without EoG/EoN had comorbid conditions. Rates of all-cause HRU were significantly higher among patients with EoG/EoN versus patients without EoG/EoN (adjusted rate ratio [95% confidence interval]: inpatient visits, 6.26 [5.26, 7.46]; outpatient visits, 1.17 [1.16, 1.19]; emergency department visits, 2.11 [1.98, 2.25]; all p < 0.001). Patients with EoG/EoN incurred significantly higher costs versus patients without EoG/EoN (adjusted mean cost difference $31,180; p < 0.001). Cost differences were largely due to outpatient (adjusted mean cost difference $14,018; p < 0.001) and inpatient (adjusted mean cost difference $11,224; p < 0.001) costs.

conclusionThe economic burden associated with EoG/EoN is substantial, with patients with EoG/EoN having a higher rate of HRU and incurring $31,180 more than patients without EoG/EoN on average. Most of the cost difference was attributable to outpatient and inpatient costs. Cost-saving strategies to lower the burden of illness in this patient population are needed.

Indexed as

Health ResourcesAgedCost of IllnessEnteritisEosinophiliaFinancial StressGastritisHealth Care CostsHumansMedicareRetrospective StudiesUnited StatesEconomic burdenEosinophilic enteritisEosinophilic gastritisHealthcare resource utilization

Identifiers

PMID35689161
PMCPMC9309124
OpenAlexW4281704676

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.