Evidence map›Paper›PMID 35689003›Full record

ArticleJournal of cancer survivorship : research and practice2023

Employment trajectories of young women with breast cancer: an ongoing prospective cohort study in Italy and Switzerland.

Karin Ribi, Eleonora Pagan, Isabella Sala, Monica Ruggeri, Nadia Bianco, Eraldo Oreste Bucci, Rossella Graffeo, Markus Borner, Monica Giordano, Lorenzo Gianni and 17 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Journal of cancer survivorship : research and practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Prognostic factors for return to work in breast cancer survivors.The Cochrane database of systematic reviews · 2025
    Pooled it
  2. Article
  3. Factors associated with employment outcomes in cancer survivors: a systematic scoping review spanning a decade of international research.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 20 institutions in 3 countries.

Karin RibiQuality of Life Office, International Breast Cancer Study Group, Bern, Switzerland. karin.ribi@etop.ibcsg.org.ORCID 0000-0003-4724-1197
Eleonora PaganUnit of Biostatistics, Epidemiology and Public Health, Department of Statistics and Quantitative Methods, University of Milan-Bicocca, Milan, Italy.
Isabella SalaUnit of Biostatistics, Epidemiology and Public Health, Department of Statistics and Quantitative Methods, University of Milan-Bicocca, Milan, Italy.
Monica RuggeriProgram for Young Patients, International Breast Cancer Study Group, Bern, Switzerland.
Nadia BiancoDivision of Medical Senology, IEO, European Institute of Oncology IRCCS, Milan, Italy.
Eraldo Oreste BucciBreast Cancer Unit, OspedaleMultiMedica, Castellanza, VA, Italy.
Rossella GraffeoOncology Institute of Southern Switzerland, EOC, Bellinzona, Switzerland.
Markus BornerDivision of Oncology (Oncocare), Klinik Engeried, Lindenhofgruppe, Bern, Switzerland.
Monica GiordanoASST-Lariana, Como, Italy.
Lorenzo GianniDepartment of Medical Oncology, Ospedale Infermi, AUSL Della Romagna, Rimini, Italy.
Manuela RabaglioDepartment of Medical Oncology, Bern University Hospital, University of Bern, Inselspital, Bern, Switzerland.
Andrea FreschiDepartment of Medical Oncology, CRO, Aviano, Italy.
Elisabetta CretellaDepartment of Medical Oncology, Azienda Sanitaria Dell'Alto Adige, Bolzano, Italy.
Elena SelesDepartment of Medical Oncology, Ospedale degli Infermi, Biella, Italy.
Alberto FarolfiDepartment of Medical Oncology, IRCCS Istituto Romagnolo Per Lo Studio Dei Tumori (IRST) "Dino Amadori", Meldola, Italy.
Edda SimonciniBreast Unit, ASST Spedali Civili Di Brescia, Brescia, Italy.
Mariangela CiccareseU.O. Oncologia Medica, Vito Fazzi Hospital, Lecce, Italy.
Daniel RauchMedical Oncology, Spital STS, Thun, Switzerland.
Adolfo FavarettoMedical Oncology Unit, Azienda ULSS2 Marca Trevigiana, Treviso, Italy.
Agnes GlausTumor- and Breast Center ZeTuP, St. Gallen, Switzerland.
Rossana BerardiDepartment of Medical Oncology, Università Politecnica Delle Marche, A.O.U. Ospedali Riuniti Di Ancona, Ancona, Italy.
Alessandra Franzetti-PellandaRadiotherapy Service, Clinica Luganese Moncucco, Lugano, Switzerland.
Vincenzo BagnardiUnit of Biostatistics, Epidemiology and Public Health, Department of Statistics and Quantitative Methods, University of Milan-Bicocca, Milan, Italy.
Shari GelberDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Ann H PartridgeDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
Aron GoldhirschInternational Breast Cancer Study Group, IEO European Institute of Oncology, IRCCS, Milan, Italy.
Olivia PaganiSwiss Group for Clinical Cancer Research (SAKK), Interdisciplinary Cancer Service Hospital Riviera-Chablais Rennaz, Vaud, Geneva University Hospitals, Lugano University, Lugano, Switzerland.
University of Milano-Bicocca · ITInternational Breast Cancer Study Group · CHAULSS 2 Marca Trevigiana · ITAzienda Sanitaria di Firenze · ITAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITAzienda Socio Sanitaria Territoriale Lariana · ITBreast Center · CHBrigham and Women's Hospital · USCentro di Riferimento Oncologico · ITClinica Luganese Moncucco · CHDana-Farber Cancer Institute · USEngeriedspital · CHEuropean Institute of Oncology · ITInstitute of Oncology Research · CHIstituti di Ricovero e Cura a Carattere Scientifico · ITIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori · ITMarche Polytechnic University · ITMultiMedica · ITOspedale degli Infermi · ITOspedale Infermi di Rimini · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDespite extensive research on cancer and work-related outcomes, evidence from longitudinal cohort studies is limited, especially in young women with breast cancer (BC). We aimed to investigate employment trajectories in young BC survivors and to identify potential factors associated with changes in work activity.

methodsThe HOHO European prospective multicenter cohort study enrolled 300 young women (≤ 40 years) with newly diagnosed BC. Women completed surveys at baseline and every 6 months for 3 years, then yearly for up to 10 years to assess, among other variables, employment status, sociodemographic, medical, and treatment data. Symptoms were assessed by the Breast Cancer Prevention Trial symptom scales and single items from the Cancer Rehabilitation Evaluation System. Univariable and multivariable multinomial logistic regression analyses identified factors associated with changes in employment status.

resultsAmong the 245 women included in this analysis, 85% were employed at the last individual post-baseline assessment (1 to 10 years). At 5 years, women had a 29.4% probability (95% CI: 23.6-35.5) of experiencing any reduction and a 14.9% probability (95% CI: 10.6-19.9) of experiencing any increase in work activities. Being enrolled in Switzerland (vs. Italy) and reporting more trouble in performing daily activities were significantly associated with work reduction.

conclusionOur results suggest that most young BC survivors remain employed in the long-term. IMPLICATIONS FOR CANCER SURVIVORS: Regular evaluation of symptoms which may interfere with daily life and identification of financial discomfort is critical in providing timely and individually tailored interventions and in limiting unwanted reductions in work activities.

Indexed as

Breast NeoplasmsCancer SurvivorsCohort StudiesEmploymentFemaleHumansItalyLongitudinal StudiesProspective StudiesSwitzerland

Identifiers

PMID35689003
OpenAlexW4281849377

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.