Evidence map›Paper›PMID 35688994›Full record

ArticleThe European journal of health economics : HEPAC : health economics in prevention and care2023

EQ-5D-5L: a value set for Romania.

Elena Olariu, Wael Mohammed, Yemi Oluboyede, Raluca Caplescu, Ileana Gabriela Niculescu-Aron, Marian Sorin Paveliu, Luke Vale

Abstract read
In one paragraph

Article in The European journal of health economics : HEPAC : health economics in prevention and care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Revisiting health state preferences after 20 years: A new EQ-5D-3L value set for the Netherlands.The European journal of health economics : HEPAC : health economics in prevention and care · 2026
    Article
  3. Article
  4. Article
  5. A Head-On Comparison of EQ-VT- and Crosswalk-Based EQ-5D-5L Value Sets.Applied health economics and health policy · 2025
    Article
  6. In varietate concordia - cluster analysis of EQ-5D-5L value sets in European Union countries.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  7. Article
  8. EQ-5D-5L value set for Norway: a hybrid model using cTTO and DCE data.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. EQ-5D-5L Value Set for Slovenia.PharmacoEconomics · 2023
    Article
  13. Population norms for the EQ-5D-3L and EQ-5D-5L in Romania.Health and quality of life outcomes · 2023
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elena OlariuHealth Economics Group, Population Health Sciences Institute, Newcastle University, Baddiley-Clark Building, Richardson Road, Newcastle upon Tyne, NE2 4AX, UK. elena.olariu@newcastle.ac.uk.ORCID http://orcid.org/0000-0002-8718-5516
Wael MohammedHealth Economics Group, Population Health Sciences Institute, Newcastle University, Baddiley-Clark Building, Richardson Road, Newcastle upon Tyne, NE2 4AX, UK.ORCID http://orcid.org/0000-0003-0370-4903
Yemi OluboyedeHealth Economics Group, Population Health Sciences Institute, Newcastle University, Baddiley-Clark Building, Richardson Road, Newcastle upon Tyne, NE2 4AX, UK.ORCID http://orcid.org/0000-0002-9891-8279
Raluca CaplescuDepartment of Statistics and Econometrics, Faculty of Economic Cybernetics, Statistics and Informatics, Bucharest University of Economic Studies, Bucharest, Romania.ORCID http://orcid.org/0000-0001-6489-171X
Ileana Gabriela Niculescu-AronDepartment of Statistics and Econometrics, Faculty of Economic Cybernetics, Statistics and Informatics, Bucharest University of Economic Studies, Bucharest, Romania.ORCID http://orcid.org/0000-0003-2902-1641
Marian Sorin PaveliuDepartment of Pharmacology and Pharmaeconomics, Faculty of General Medicine, Titu Maiorescu University, Bucharest, Romania.ORCID http://orcid.org/0000-0002-0702-1715
Luke ValeHealth Economics Group, Population Health Sciences Institute, Newcastle University, Baddiley-Clark Building, Richardson Road, Newcastle upon Tyne, NE2 4AX, UK.ORCID http://orcid.org/0000-0001-8574-8429

Funding

EuroQol Research Foundation 20180030R1H2020 Marie Skłodowska-Curie Actions 748612
6 · The paper itself

Abstract

objectiveWe aimed to develop an EQ-5D-5L value set for Romania.

methodsIn line with the EuroQoL standardized valuation protocol, computer-assisted interviews were conducted face-to-face in a representative sample in Romania (November 2018-November 2019). Valuation methods included composite time trade-off and discrete choice experiment tasks. Several models were tested, including models that accounted for data censoring, panel structure of the data, heteroscedasticity, conditional logit, and hybrid models. The final model was selected based on logical consistency, theoretical considerations, and use of all available data. We compared our value set with other value sets from Central and Eastern Europe region.

resultsData from 1493 respondents was used to estimate the value set. A censored hybrid model corrected for heteroscedasticity was selected to represent the value set. The highest decrements in utility were observed for the pain/discomfort dimension (0.375), followed by the mobility dimension (0.293). Health utilities ranged from 1.000 to - 0.323 and 1.3% of the values were negative. The model was corrected with survey weights to better reflect the representativeness of the sample, but the first two coefficients of the self-care dimension stopped being logically consistent. Differences were found between the Romanian, Hungarian and Polish EQ-5D-5L value sets. Good agreement was noted with the Romanian EQ-5D-3L value set, with a swap between pain/discomfort and mobility in ranking of dimensions.

conclusionA value set for EQ-5D-5L is now available for Romania. This will push one-step further the development of health technology assessment and encourage more health-related quality-of-life research to be conducted locally.

Indexed as

Health StatusQuality of LifeHumansPolandRomaniaSurveys and QuestionnairesEQ-5D-5LHealth technology assessmentUtilityValue set

Identifiers

PMID35688994
PMCPMC10060331

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.