ArticleScientific reports2022
Deficits in spontaneous and stimulus-dependent retrieval as an early sign of abnormal aging.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.
- The Relative Accuracy of Different Methods for Measuring Mind Wandering Subtypes: A Systematic Review.Brain and behavior · 2025Pooled it
- Early detection of cognitive impairment in the general population through a digital tool targeting the prospective memory. A pilot study.Annals of medicine · 2025Article
- Using objective and subjective measures of mind wandering to predict progression to development of cognitive impairment and test associations with Alzheimer disease biomarkers.Journal of clinical and experimental neuropsychology · 2025Article
- Investigating the relationship between periodontitis and specific memory processes in the search for cognitive markers of Alzheimer's disease risk.Scientific reports · 2023Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Research on early cognitive markers of Alzheimer's disease is primarily focused on episodic memory tests that involve deliberate retrieval. Our purpose was to provide clear evidence to support a novel Spontaneous Retrieval Deficit hypothesis, which predicts that people at pre-clinical stages of dementia, including those with amnestic Mild Cognitive Impairment (aMCI), are particularly impaired on tasks based on spontaneous retrieval. We compared 27 aMCI individuals and 27 healthy controls on mind-wandering while performing a task during which there were exposed to either highly meaningful or unmeaningful pictures. The substantial reduction in mind-wandering among individuals with aMCI was found with exposure to highly meaningful stimuli, but not to unmeaningful pictures, and it was most pronounced for past-oriented thoughts, i.e., involuntary autobiographical memories. Those findings provide strong support for this novel hypothesis, and show that it is the spontaneous, but bottom-up and cue-driven processes, for which meaningful environmental stimuli are crucial, that are very promising early markers of the disease.
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Registered trials
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