Evidence map›Paper›PMID 35688918›Full record

ArticleScientific reports2022

Co-administration of Lactobacillus gasseri KBL697 and tumor necrosis factor-alpha inhibitor infliximab improves colitis in mice.

Dae Hee Han, Woon-Ki Kim, Cheonghoon Lee, SungJun Park, Kiuk Lee, Sung Jae Jang, GwangPyo Ko

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Dae Hee Han *Department of Environmental Health Sciences, Graduate School of Public Health, Seoul National University, Seoul, Republic of Korea.
Woon-Ki Kim *Department of Environmental Health Sciences, Graduate School of Public Health, Seoul National University, Seoul, Republic of Korea.
Cheonghoon LeeDepartment of Environmental Health Sciences, Graduate School of Public Health, Seoul National University, Seoul, Republic of Korea.
SungJun ParkDepartment of Environmental Health Sciences, Graduate School of Public Health, Seoul National University, Seoul, Republic of Korea.
Kiuk LeeKoBioLabs, Inc, Seoul, Republic of Korea.
Sung Jae JangDepartment of Environmental Health Sciences, Graduate School of Public Health, Seoul National University, Seoul, Republic of Korea.
GwangPyo KoDepartment of Environmental Health Sciences, Graduate School of Public Health, Seoul National University, Seoul, Republic of Korea. gko@snu.ac.kr.
Seoul National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) refers to disorders involving chronic inflammation of the gastrointestinal tract. Well-established treatments for IBD have not yet to be suggested. To address this gap, we investigated the effects of co-administration of Lactobacillus gasseri (L. gasseri) KBL697 and infliximab (IFX), the first approved tumor necrosis factor (TNF)-alpha inhibitor, on the dextran sodium sulfate-induced colitis mouse model. 2 × 10

Indexed as

ColitisInflammatory Bowel DiseasesLactobacillus gasseriAnimalsColonCytokinesDextran SulfateDisease Models, AnimalFemaleImmunologic FactorsInfliximabMiceMice, Inbred C57BLTumor Necrosis Factor-alphaCytokinesDextran SulfateImmunologic FactorsInfliximabTumor Necrosis Factor-alpha

Identifiers

PMID35688918
PMCPMC9187735
OpenAlexW4281985095

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.