Evidence map›Paper›PMID 35688890›Full record

ArticleScientific reports2022

Multi-modal and multi-scale clinical retinal imaging system with pupil and retinal tracking.

Muhammad Faizan Shirazi, Jordi Andilla, Nicolas Lefaudeux, Claudia Valdes, Florian Schwarzhans, Marine Durand, Konstantinos Ntatsis, Danilo Andrade De Jesus, Luisa Sanchez Brea, Kiyoko Gocho and 13 more

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Next-generation molecular imaging of cardiac fibrosis.The international journal of cardiovascular imaging · 2026
    Review
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  6. Biomedical optics express · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Muhammad Faizan ShiraziCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Jordi AndillaICFO-Institut de Ciencies Fotoniques, The Barcelona Institute of Science and Technology, 08860, Castelldefels, Barcelona, Spain.
Nicolas LefaudeuxImagine Eyes, Orsay, France.
Claudia ValdesICFO-Institut de Ciencies Fotoniques, The Barcelona Institute of Science and Technology, 08860, Castelldefels, Barcelona, Spain.
Florian SchwarzhansCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Marine DurandImagine Eyes, Orsay, France.
Konstantinos NtatsisBiomedical Imaging Group Rotterdam, Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands.
Danilo Andrade De JesusBiomedical Imaging Group Rotterdam, Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands.
Luisa Sanchez BreaBiomedical Imaging Group Rotterdam, Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands.
Kiyoko GochoCHNO Des Quinze-Vingts, INSERM-DGOS CIC 1423, 28 rue de Charenton, Paris, France.
Josselin GautierCHNO Des Quinze-Vingts, INSERM-DGOS CIC 1423, 28 rue de Charenton, Paris, France.
Christina Eckmann-HansenRigshospitalet, Department of Ophthalmology, University of Copenhagen, Copenhagen, Denmark.
Marie Elise Wistrup TormRigshospitalet, Department of Ophthalmology, University of Copenhagen, Copenhagen, Denmark.
Abdullah AminiRigshospitalet, Department of Ophthalmology, University of Copenhagen, Copenhagen, Denmark.
Stefan KleinBiomedical Imaging Group Rotterdam, Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands.
Theo Van WalsumBiomedical Imaging Group Rotterdam, Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands.
Kate GrieveCHNO Des Quinze-Vingts, INSERM-DGOS CIC 1423, 28 rue de Charenton, Paris, France.
Michel PaquesCHNO Des Quinze-Vingts, INSERM-DGOS CIC 1423, 28 rue de Charenton, Paris, France.
Michael LarsenRigshospitalet, Department of Ophthalmology, University of Copenhagen, Copenhagen, Denmark.
Pablo Loza-AlvarezICFO-Institut de Ciencies Fotoniques, The Barcelona Institute of Science and Technology, 08860, Castelldefels, Barcelona, Spain.
Xavier LevecqImagine Eyes, Orsay, France.
Nicolas ChateauImagine Eyes, Orsay, France.
Michael PircherCenter for Medical Physics and Biomedical Engineering, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria. michael.pircher@meduniwien.ac.at.

Funding

Marie Curie 754510
6 · The paper itself

Abstract

We present a compact multi-modal and multi-scale retinal imaging instrument with an angiographic functional extension for clinical use. The system integrates scanning laser ophthalmoscopy (SLO), optical coherence tomography (OCT) and OCT angiography (OCTA) imaging modalities and provides multi-scale fields of view. For high resolution, and high lateral resolution in particular, cellular imaging correction of aberrations by adaptive optics (AO) is employed. The entire instrument has a compact design and the scanning head is mounted on motorized translation stages that enable 3D self-alignment with respect to the subject's eye by tracking the pupil position. Retinal tracking, based on the information provided by SLO, is incorporated in the instrument to compensate for retinal motion during OCT imaging. The imaging capabilities of the multi-modal and multi-scale instrument were tested by imaging healthy volunteers and patients.

Indexed as

PupilRetinaHumansOphthalmoscopyOptics and PhotonicsTomography, Optical Coherence

Identifiers

PMID35688890
PMCPMC9187716

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.