Evidence map›Paper›PMID 35688606›Full record

ArticleStatistics in medicine2022

Markov neighborhood regression for statistical inference of high-dimensional generalized linear models.

Lizhe Sun, Faming Liang

Open access · greenAbstract read
In one paragraph

Article in Statistics in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Extended fiducial inference: toward an automated process of statistical inference.Journal of the Royal Statistical Society. Series B, Statistical methodology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Lizhe SunDepartment of Statistics, Purdue University, West Lafayette, Indiana, USA.ORCID 0000-0003-4860-4957
Faming LiangDepartment of Statistics, Purdue University, West Lafayette, Indiana, USA.ORCID 0000-0002-1177-5501
Purdue University West Lafayette · US

Funding

An Imputation-Consistency Algorithm for Biomedical Complex Data AnalysisR01GM126089 · NIGMS · PURDUE UNIVERSITY · PI LIANG, FAMING · 2018 to 2021
$1.2M
Equivalent Partial Correlation Methods for Integrative Genetic Network Analysis R01GM117597 · NIGMS · UNIVERSITY OF FLORIDA · PI LIANG, FAMING · 2015 to 2017
$1.0M
NIGMS NIH HHS R01 GM117597NIGMS NIH HHS R01-GM117597NIGMS NIH HHS R01 GM126089NIGMS NIH HHS R01-GM126089
6 · The paper itself

Abstract

High-dimensional inference is one of fundamental problems in modern biomedical studies. However, the existing methods do not perform satisfactorily. Based on the Markov property of graphical models and the likelihood ratio test, this article provides a simple justification for the Markov neighborhood regression method such that it can be applied to statistical inference for high-dimensional generalized linear models with mixed features. The Markov neighborhood regression method is highly attractive in that it breaks the high-dimensional inference problems into a series of low-dimensional inference problems. The proposed method is applied to the cancer cell line encyclopedia data for identification of the genes and mutations that are sensitive to the response of anti-cancer drugs. The numerical results favor the Markov neighborhood regression method to the existing ones.

Indexed as

Models, StatisticalHumansLikelihood FunctionsLinear ModelsMarkov ChainsRegression Analysisconfidence intervalgraphical modellikelihood ratio testnodewise regression

Identifiers

PMID35688606
PMCPMC9427730
OpenAlexW4281998186

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.