Evidence map›Paper›PMID 35688577›Full record

ArticleBMJ case reports2022

Monoclonal gammopathy of undetermined significance causing large vessel vasculitis.

Edward George Alcorn, Lauren Floyd, Ajay Dhaygude

Open access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Edward George AlcornDepartment of Nephrology, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, Lancashire, UK ed.alcorn260@gmail.com.ORCID http://orcid.org/0000-0002-9499-8363
Lauren FloydDepartment of Nephrology, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, Lancashire, UK.
Ajay DhaygudeDepartment of Nephrology, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, Lancashire, UK.
Lancashire Teaching Hospitals NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A man in his late 50s presented with unilateral pain and discolouration of his fourth and fifth toes suggestive of digital ischaemia. He had a medical history of two unprovoked venous thromboembolisms in the preceding 18 months and a history of monoclonal gammopathy of undetermined significance (MGUS). A CT scan showed evidence of large vessels vasculitis in the absence of circulating antineutrophil cytoplasmic antibodies. Biopsy of the toes showed evidence of light chain and immunoglobulin deposition on immunofluorescence suggesting vasculitis secondary to his haematological diagnosis of MGUS. The patient was treated with high dose glucocorticoids and immunosuppressive treatment with a significant improvement in his symptoms and features of digital ischaemia.

Indexed as

Monoclonal Gammopathy of Undetermined SignificanceVasculitisAntibodies, Antineutrophil CytoplasmicGlucocorticoidsHumansIschemiaMaleAntibodies, Antineutrophil CytoplasmicGlucocorticoidsHaematology (incl blood transfusion)Malignant and Benign haematologyVasculitis

Identifiers

PMID35688577
PMCPMC9189764
OpenAlexW4281764995

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.