Evidence map›Paper›PMID 35688435›Full record

SynthesisThe clinical respiratory journal2022

Osteoporosis in COPD patients: Risk factors and pulmonary rehabilitation.

Yujuan Li, Hongchang Gao, Lei Zhao, Jinrui Wang

Registry-linked trialOpen access · goldAbstract readSystematic Review
In one paragraph

Synthesis in The clinical respiratory journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06308302 (Comparative Effects of Inspiratory Muscle Training vs Expiratory Muscle Training Along With Aerobic Interval Training on Functional Performance and Fatigue Level in COPD Patients), which is not on this map. Cited by 43 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 3 pooled it
9.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06308302 nacompletednot on this mapstarted 2023, after this paper: background citation

Comparative Effects of Inspiratory Muscle Training vs Expiratory Muscle Training Along With Aerobic Interval Training on Functional Performance and Fatigue Level in COPD Patients

TypeinterventionalSponsorRiphah International UniversityRan2023 to 2024Enrolled53ConditionsCOPDArmsGroup A (Inspiratory Muscles Training + Aerobic Interval Training), Group B (Expiratory Muscles Training +Aerobic Interval Training)
3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 3 syntheses or guidelines pooled it, 65 citations in OpenAlex.

  1. Pooled it
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  4. Article
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  6. Article
  7. Review
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  11. Development and internal validation of a clinical-radiological nomogram for osteoporosis screening: A cohort retrospective study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  12. Review
  13. Case report on possible causes of severe osteoporosis: diffuse panbronchiolitis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Article
  14. Article
  15. Short-Term Outcomes of Noncemented Total Knee Arthroplasty in Patients With Morbid Obesity.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025
    Article
  16. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yujuan LiDepartment of Pulmonary and Critical Care Medicine, Shanghai Pudong New Area Gongli Hospital, Shanghai, China.
Hongchang GaoDepartment of Pulmonary and Critical Care Medicine, Shanghai Pudong New Area Gongli Hospital, Shanghai, China.
Lei ZhaoDepartment of Pulmonary and Critical Care Medicine, Shanghai Pudong New Area Gongli Hospital, Shanghai, China.
Jinrui WangDepartment of Pulmonary and Critical Care Medicine, Shanghai Pudong New Area Gongli Hospital, Shanghai, China.
Second Military Medical University · CNShanghai Pudong New Area Gongli Hospital · CN

Funding

Pudong New Area Health Commission Project PW2020A-19Shanghai Health Commission Project 202040191
6 · The paper itself

Abstract

objectivesTo present a review on the pathogenesis, risk factor and treatment of chronic obstructive pulmonary disease complicated with osteoporosis and provide new ideas for the diagnosis and treatment. DATA SOURCE: A systematic search is carried out using keywords as chronic obstructive pulmonary disease, osteoporosis, risk factors, and pulmonary rehabilitation.

resultsPatients with chronic obstructive pulmonary disease have a high prevalence of osteoporosis and a high risk of fracture. The mechanisms of osteoporosis in COPD patients are associated with general risk factors, such as smoking, reduced physical activity, low weight, and disease-specific risk factors, such as systemic inflammatory, Vitamin D deficiency, use of glucocorticoid, anemia, hypoxemia, and hypercapnia. The treatment of osteoporosis in COPD emphasizes comprehensive intervention, which mainly include basic treatment and anti-osteoporosis drugs. Noticeably, pulmonary rehabilitation program is an important part of treatment.

conclusionsThis work summarizes the pathogenesis, risk factor, prevention, and treatment of chronic obstructive pulmonary disease complicated with osteoporosis, and the latest progress of studies on chronic obstructive pulmonary disease and osteoporosis is discussed.

Indexed as

Fractures, BoneOsteoporosisPulmonary Disease, Chronic ObstructiveVitamin D DeficiencyHumansRisk Factorschronic obstructive pulmonary diseasefractureosteoporosisprevalencepulmonary rehabilitationrisk factors

Identifiers

PMID35688435
PMCPMC9329018
OpenAlexW4281722635

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.