Evidence map›Paper›PMID 35687545›Full record

Observational studyPloS one2022

Clinical characteristics and outcomes of COVID-19 patients in Bali, Indonesia.

Sri Masyeni, Erni Juwita Nelwan, Rois Muqsith Fatawy, Surya Wibawa, Putu Arya Nugraha, Jarwa Antara, Adi Suparta, D G Wedha Asmara, L G Sri Yenny, A A G Budhitresna and 21 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Determinant Factors of Mortality in Pre-elderly and Elderly Patients With COVID-19 in Jakarta, Indonesia.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors at 5 institutions in 1 country.

Sri MasyeniDepartment of Internal Medicine, Faculty of Medicine and Health Sciences, Universitas Warmadewa/Sanjiwani Hospital, Bali, Indonesia.
Erni Juwita NelwanInfectious Disease and Immunology Research Center, Indonesia Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.ORCID 0000-0003-4064-5412
Rois Muqsith FatawyInfectious Disease and Immunology Research Center, Indonesia Medical Education and Research Institute, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
Surya WibawaBali Mandara Hospital, Bali, Indonesia.
Putu Arya NugrahaDepartment of Internal Medicine, Pratama Giri Emas Hospital, Bali, Indonesia.
Jarwa AntaraDepartment of Internal Medicine, Nyitdah Tabanan Hospital, Bali, Indonesia.
Adi SupartaMangusada Badung Hospital, Bali, Indonesia.
D G Wedha AsmaraDepartment of Internal Medicine, Faculty of Medicine and Health Sciences, Universitas Warmadewa/Sanjiwani Hospital, Bali, Indonesia.
L G Sri YennyDepartment of Internal Medicine, Faculty of Medicine and Health Sciences, Universitas Warmadewa/Sanjiwani Hospital, Bali, Indonesia.
A A G BudhitresnaDepartment of Internal Medicine, Faculty of Medicine and Health Sciences, Universitas Warmadewa/Sanjiwani Hospital, Bali, Indonesia.
Dewi ArimasDepartment of Clinical Pathology, Singaraja Hospital, Bali, Indonesia.
Dewi IndrianiKlungkung Semarapura Hospital, Bali, Indonesia.
Kmg ParwataKlungkung Semarapura Hospital, Bali, Indonesia.
Ketut SutarjanaBangli Hospital, Bali, Indonesia.
Eka SugiarthaBangli Hospital, Bali, Indonesia.
Siska KahariDepartment of Internal Medicine, Nyitdah Tabanan Hospital, Bali, Indonesia.
Clareza Arief WardhanaDepartment of Clinical Pathology, Faculty of Medicine, Universitas Udayana, Bali, Indonesia.
A A G IndraningratDepartment of Internal Medicine, Faculty of Medicine and Health Sciences, Universitas Warmadewa/Sanjiwani Hospital, Bali, Indonesia.ORCID 0000-0002-8679-6016
Kadek MulyantariDepartment of Clinical Pathology, Faculty of Medicine, Universitas Udayana, Bali, Indonesia.
Arya Widiyana PasekMangusada Badung Hospital, Bali, Indonesia.
Oka PutrawanMangusada Badung Hospital, Bali, Indonesia.
Nyoman Trisna YustianiDepartment of Internal Medicine, Pratama Giri Emas Hospital, Bali, Indonesia.
Gede WardanaBalai Pelatihan Kesehatan Bali, Bali, Indonesia.
Made Indra WijayaDepartment of Internal Medicine, Faculty of Medicine and Health Sciences, Universitas Warmadewa/Sanjiwani Hospital, Bali, Indonesia.ORCID 0000-0003-1733-9409
Suka AryanaDepartment of Internal Medicine, Sanglah Hospital, Faculty of Medicine, Universitas Udayana, Bali, Indonesia.
Yuli GayatriDepartment of Internal Medicine, Sanglah Hospital, Faculty of Medicine, Universitas Udayana, Bali, Indonesia.
Dewi Dian SukmawatiDepartment of Internal Medicine, Sanglah Hospital, Faculty of Medicine, Universitas Udayana, Bali, Indonesia.
Ketut SuastikaDepartment of Internal Medicine, Sanglah Hospital, Faculty of Medicine, Universitas Udayana, Bali, Indonesia.
Tuti Parwati MeratiDepartment of Internal Medicine, Sanglah Hospital, Faculty of Medicine, Universitas Udayana, Bali, Indonesia.
Made BaktaDepartment of Internal Medicine, Sanglah Hospital, Faculty of Medicine, Universitas Udayana, Bali, Indonesia.
Raka WidianaDepartment of Internal Medicine, Sanglah Hospital, Faculty of Medicine, Universitas Udayana, Bali, Indonesia.
Udayana University · IDWarmadewa University · IDUniversitas Tabanan · IDUniversity of Indonesia · IDBalai Arkeologi Sulawesi Selatan · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe spectrum of illness and outcomes of coronavirus disease 2019 (COVID-19) patients may vary. This study reports the characteristics of COVID-19 patients in Bali, Indonesia, and evaluates the diagnostic value of their clinical symptoms.

methodThis observational study was conducted in eight hospitals. The patients were classified as non-severe COVID-19, severe COVID-19, and non-COVID-19. Demographics, clinical, laboratory, and radiologic characteristics, and outcomes of COVID-19 patients were collected. Factors associated with the severity and outcomes were assessed using the chi-squared test or ANOVA when appropriate. We also compared the clinical features of non-severe COVID-19 and non-COVID-19 patients to evaluate the diagnostic accuracy.

resultsThis study included 92 patients: 41 non-COVID-19 and 51 COVID-19 patients, comprising 45 non-severe and six severe cases. The most common symptoms of COVID-19 were cough (47.1%), fever (31.0%), and dyspnea (25.3%). Cough, fatigue, and anosmia have high accuracy, and combining these complaints in clinical diagnostics offered a higher accuracy in predicting COVID-19 patients (60.1%). We found lower lymphocyte counts and interleukin-1R levels and higher levels of C-reactive protein, interleukin-6, and interleukin-8 in severe compared than in non-severe COVID-19 patients. Lactate dehydrogenase was associated with intensive care unit admission and ventilator use, while other markers such as neutrophil-lymphocyte ratio, C-reactive protein, and interleukin-6 were not.

conclusionA battery of symptoms, including cough, fatigue, and anosmia, is likely associated with COVID-19 in Bali. Clinicians should be aware of these symptoms to ensure a prompt diagnostic test for COVID-19, beyond other causes of acute febrile illnesses.

Indexed as

COVID-19AnosmiaCoughC-Reactive ProteinFatigueFeverHumansIndonesiaInterleukin-6Retrospective StudiesSARS-CoV-2C-Reactive ProteinInterleukin-6

Identifiers

PMID35687545
PMCPMC9187108
OpenAlexW4281741527

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.