Evidence map›Paper›PMID 35687485›Full record

ArticleAmerican journal of respiratory and critical care medicine2022

CD38 Mediates Lung Fibrosis by Promoting Alveolar Epithelial Cell Aging.

Huachun Cui, Na Xie, Sami Banerjee, Tapan Dey, Rui-Ming Liu, Veena B Antony, Yan Y Sanders, Taylor S Adams, Jose L Gomez, Victor J Thannickal and 2 more

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
9.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
  2. NADAging cell · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
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  11. Article
  12. Article
  13. Review
  14. Mechanisms and markers of lung ageing in health and disease.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  15. Review
  16. Pulmonary fibrosis: from mechanisms to therapies.Journal of translational medicine · 2025
    Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Huachun CuiDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Na XieDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Sami BanerjeeDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Tapan DeyDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Rui-Ming LiuDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Veena B AntonyDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Yan Y SandersDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.
Taylor S AdamsPulmonary, Critical Care and Sleep Medicine, Yale School of Medicine, New Haven, Connecticut; and.
Jose L GomezPulmonary, Critical Care and Sleep Medicine, Yale School of Medicine, New Haven, Connecticut; and.
Victor J ThannickalDepartment of Medicine, Tulane University School of Medicine, New Orleans, Louisiana.
Naftali KaminskiPulmonary, Critical Care and Sleep Medicine, Yale School of Medicine, New Haven, Connecticut; and.ORCID 0000-0001-5917-4601
Gang LiuDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama.ORCID 0000-0003-2615-131X
University of Alabama at Birmingham · USYale University · USTulane University · US

Funding

Therapeutic Targeting of the Myofibroblast in Fibrotic Lung DiseaseP01HL114470 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI THANNICKAL, VICTOR J. · 2013 to 2022
$17.8M
Project 5 Nano-micro Hybrid Fibrous Materials for Containment Removal and Site RemediationP42ES027723 · NIEHS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ANTONY, VEENA B. · 2020 to 2024
$6.7M
Genomic Analysis of Tissue and Cellular Heterogeneity in IPFR01HL127349 · NHLBI · YALE UNIVERSITY · PI BENOS, PANAGIOTIS V, KAMINSKI, NAFTALI · 2015 to 2025
$5.9M
Program on cellular metabolism and lung fibrosisR35HL135830 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LIU, GANG · 2017 to 2023
$5.2M
Systems Biology of a MicroRNA Network in Neutrophilic AsthmaR01HL153604 · NHLBI · YALE UNIVERSITY · PI GOMEZ-VILLALOBOS, JOSE LUIS · 2020 to 2024
$3.4M
Epithelial Protective Effects of Thyroid Hormone Signaling in FibrosisR01HL141852 · NHLBI · YALE UNIVERSITY · PI KAMINSKI, NAFTALI · 2019 to 2022
$3.4M
Metabolic Landscape of the Aging LungR01HL152246 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARNES, JARROD W., THANNICKAL, VICTOR J. · 2020 to 2023
$3.2M
Normal Aging Lung Cell Atlas (NALCA)U01HL145567 · NHLBI · YALE UNIVERSITY · PI KAMINSKI, NAFTALI · 2019 to 2022
$2.8M
Mir-29 mimicry as a therapy for pulmonary fibrosisUH2HL123886 · NHLBI · YALE UNIVERSITY · PI KAMINSKI, NAFTALI · 2014 to 2015
$2.7M
Environmental Cadmium and COPDR01ES029981 · NIEHS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ANTONY, VEENA B. · 2018 to 2022
$2.5M
Histone H4 Lysine16 Acetylation in Aging and Lung FibrosisR01AG050567 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SANDERS, YAN · 2016 to 2020
$1.5M
Regulation of Neutrophilic Airway Inflammation by miR-223-3pR03HL154275 · NHLBI · YALE UNIVERSITY · PI GOMEZ-VILLALOBOS, JOSE LUIS · 2020 to 2021
$168k
BLRD VA I01 BX003056NHLBI NIH HHS P01 HL114470NHLBI NIH HHS R01 HL127349NHLBI NIH HHS R01 HL141852NHLBI NIH HHS R01 HL152246NHLBI NIH HHS R01 HL153604NHLBI NIH HHS R03 HL154275NHLBI NIH HHS R35 HL135830NHLBI NIH HHS U01 HL145567NHLBI NIH HHS UH2 HL123886NIA NIH HHS R01 AG050567NIEHS NIH HHS P42 ES027723NIEHS NIH HHS R01 ES029981NIH HHS P01HL114470NIH HHS R01AG050567
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alveolar Epithelial CellsIdiopathic Pulmonary FibrosisAgingAnimalsBleomycinCellular SenescenceHumansLungMiceNADBleomycinNADalveolar epithelial cellCD38nicotinamide adenine dinucleotidepulmonary fibrosissenescence

Identifiers

PMID35687485
PMCPMC12039157
OpenAlexW4281713270

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.