Evidence map›Paper›PMID 35687312›Full record

ArticleAging clinical and experimental research2022

Social network and the risk for developing mild cognitive impairment and dementia among older adults.

Hrafnhildur Eymundsdottir, Sigurveig Sigurdardottir, Alfons Ramel, Pálmi V Jonsson, Vilmundur Gudnason, Lenore Launer, Milan Chang

Open access · greenAbstract read
In one paragraph

Article in Aging clinical and experimental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Hrafnhildur EymundsdottirThe Icelandic Gerontological Research Center, The National University Hospital of Iceland, Tungata 26, 101, Reykjavik, Iceland. hrafnhildureymunds@gmail.com.ORCID http://orcid.org/0000-0002-5614-0315
Sigurveig SigurdardottirFaculty of Social Science, University of Iceland, Reykjavik, Iceland.
Alfons RamelThe Icelandic Gerontological Research Center, The National University Hospital of Iceland, Tungata 26, 101, Reykjavik, Iceland.
Pálmi V JonssonFaculty of Medicine, University of Iceland, Reykjavik, Iceland.
Vilmundur GudnasonFaculty of Medicine, University of Iceland, Reykjavik, Iceland.
Lenore LaunerLaboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
Milan ChangThe Icelandic Gerontological Research Center, The National University Hospital of Iceland, Tungata 26, 101, Reykjavik, Iceland.
University of Iceland · ISNational Institutes of Health · USNational University Hospital of Iceland · IS

Funding

Age, Gene/environment Susceptibility Study In Iceland - Ocular ComponentZIAEY000401 · NEI · NATIONAL EYE INSTITUTE · PI COTCH, MARY FRANCES · 2009 to 2020
$3.3M
Brain aging and cardiovascular risk factors and diseaseZIAAG007480 · NIA · NATIONAL INSTITUTE ON AGING · PI LAUNER, LENORE J · 2011 to 2025
$2.7M
Age, Gene/Environment Susceptibility StudyZ01AG007380 · NIA · NATIONAL INSTITUTE ON AGING · PI HARRIS, TAMARA B. · 2006 to 2008
$1.3M
0 0Intramural NIH HHS Z01 AG007380Intramural NIH HHS Z99 AG999999Intramural NIH HHS ZIA EY000401
6 · The paper itself

Abstract

backgroundThis study aimed to investigate the longitudinal associations between social network (SN) and the risk of lower cognitive function, mild cognitive impairment (MCI), and dementia among cognitively normal individuals 65 years and older.

methodsData from the Age, Gene/Environment Susceptibility (AGES) Reykjavik Study on 2816 participants (aged 65 to 96 years) were used to examine the associations using multiple logistic and linear regression models. SN included questions on frequency of contact with family and friends as well as information on marital status, resulting in a score ranging from 0 (poor social network) to 3 (good social network). Cognitive function outcomes included the speed of processing (SP), executive function (EF) and memory function (MF). MCI and dementia were diagnosed using a detailed assessment according to international guidelines.

resultsAt baseline 0.5, 7.0, 41.7 and 50.8% reported a score of 0, 1, 2 and 3, respectively. During a mean follow-up time of 5.2 years, 7.1% (n = 188) of cognitively intact participants developed MCI and 3.0% (n = 79) developed dementia. Longitudinal analyses demonstrated that participants who had low SN were significantly more likely to have declines in MF (β = - 0.533, P = 0.014) compared to high SN. Social networks were not independently associated with the decline of SP and EF during follow-up. According to fully adjusted models using logistic regression, SN was significantly associated with incidence risk of MCI (OR = 2.030, P = 0.014 and OR = 1.847 P = 0.001). These associations were largely independent of other lifestyle factors, depression and genetic disposition.

conclusionsCommunity-dwelling older adults who have poor social networks have a higher risk of declining memory function as well as a higher risk of mild cognitive impairment than older adults who have a higher social network. This study included numbers of relevant covariates in the study analysis, thereby significantly contributing to the literature on cognitive aging.

Indexed as

Cognitive DysfunctionDementiaAgedAged, 80 and overCognitionExecutive FunctionHumansSocial NetworkingCognitive agingExecutive function and Memory functionSocial networksSpeed of processing

Identifiers

PMID35687312
PMCPMC12742287
OpenAlexW4281887791

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.