Evidence map›Paper›PMID 35686978›Full record

ArticleThe CRISPR journal2022

CRISPR-AsCas12a Efficiently Corrects a

Simona Torriano, Edouard Baulier, Alejandro Garcia Diaz, Barbara Corneo, Debora B Farber

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The CRISPR journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Coenzyme QFree radical biology & medicine · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Simona TorrianoDepartment of Ophthalmology, UCLA School of Medicine, Jules Stein Eye Institute, Los Angeles, California, USA.ORCID 0000-0002-1095-5279
Edouard BaulierDepartment of Ophthalmology, UCLA School of Medicine, Jules Stein Eye Institute, Los Angeles, California, USA.
Alejandro Garcia DiazStem Cell Core, Columbia Stem Cell Initiative, Columbia University Irving Medical Center, New York, New York, USA.
Barbara CorneoStem Cell Core, Columbia Stem Cell Initiative, Columbia University Irving Medical Center, New York, New York, USA.ORCID 0000-0001-5189-6749
Debora B FarberDepartment of Ophthalmology, UCLA School of Medicine, Jules Stein Eye Institute, Los Angeles, California, USA.
Columbia University Irving Medical Center · USDoheny Eye Institute · USUCLA Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mutations in the

Indexed as

Albinism, OcularInduced Pluripotent Stem CellsCRISPR-Cas SystemsEye ProteinsGene EditingHumansMembrane GlycoproteinsMutationEye ProteinsGPR143 protein, humanMembrane Glycoproteins

Identifiers

PMID35686978
PMCPMC9233509
OpenAlexW4281746466

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.