Evidence map›Paper›PMID 35686555›Full record

ArticleMolecular medicine reports2022

Optimal combination of cationic lipid and phospholipid in cationic liposomes for gene knockdown in breast cancer cells and mouse lung using siRNA lipoplexes.

Yoshiyuki Hattori, Min Tang, Satomi Torii, Kana Tomita, Ayane Sagawa, Nodoka Inoue, Reo Yamagishi, Kei-Ichi Ozaki

Open access · hybridAbstract read
In one paragraph

Article in Molecular medicine reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Pharmaceutics · 2023
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yoshiyuki HattoriDepartment of Molecular Pharmaceutics, Hoshi University, Tokyo 142-8501, Japan.
Min TangDepartment of Molecular Pharmaceutics, Hoshi University, Tokyo 142-8501, Japan.
Satomi ToriiDepartment of Molecular Pharmaceutics, Hoshi University, Tokyo 142-8501, Japan.
Kana TomitaDepartment of Molecular Pharmaceutics, Hoshi University, Tokyo 142-8501, Japan.
Ayane SagawaDepartment of Molecular Pharmaceutics, Hoshi University, Tokyo 142-8501, Japan.
Nodoka InoueDepartment of Molecular Pharmaceutics, Hoshi University, Tokyo 142-8501, Japan.
Reo YamagishiDepartment of Molecular Pharmaceutics, Hoshi University, Tokyo 142-8501, Japan.
Kei-Ichi OzakiDepartment of Molecular Pathology, Faculty of Pharmaceutical Sciences, Doshisha Women's College of Liberal Arts, Kodo, Kyotanabe, Kyoto 610-0395, Japan.
Hoshi University · JPDoshisha Women's College of Liberal Arts · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Formulation of cationic liposomes is a key factor that determine the gene knockdown efficiency by cationic liposomes/siRNA complexes (siRNA lipoplexes). Here, to determine the optimal combination of cationic lipid and phospholipid in cationic liposomes for

Indexed as

Gene Knockdown TechniquesLiposomesAnimalsCationsFemaleHumansLuciferasesLungMCF-7 CellsMicePhosphatidylcholinesPhosphatidylethanolaminesPhospholipidsRNA, Small InterferingTransfectionCationsLiposomesLuciferasesPhosphatidylcholinesPhosphatidylethanolaminesPhospholipidsRNA, Small Interferingcationic liposomegene knockdownlungphospholipidsiRNA delivery

Identifiers

PMID35686555
PMCPMC9218728
OpenAlexW4281765400

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.