Evidence map›Paper›PMID 35686373›Full record

ArticleThe clinical respiratory journal2022

The combined effect of exposures to vapours, gases, dusts, fumes and tobacco smoke on current asthma.

Hanna Hisinger-Mölkänen, Hannu Kankaanranta, Tari Haahtela, Anssi Sovijärvi, Leena Tuomisto, Heidi Andersén, Ari Lindqvist, Helena Backman, Arnulf Langhammer, Eva Rönmark and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The clinical respiratory journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 3 countries.

Hanna Hisinger-MölkänenUniversity of Helsinki, Helsinki, Finland.ORCID https://orcid.org/0000-0003-2293-0279
Hannu KankaanrantaDepartment of Respiratory Medicine, Seinäjoki Central Hospital, Seinäjoki, Finland.
Tari HaahtelaSkin and Allergy Hospital, Helsinki University Hospital, University of Helsinki, Helsinki, Finland.
Anssi SovijärviUniversity of Helsinki, Helsinki, Finland.
Leena TuomistoDepartment of Respiratory Medicine, Seinäjoki Central Hospital, Seinäjoki, Finland.
Heidi AndersénThoracic Oncology Unit, Tema Cancer, Karolinska University Hospital, Stockholm, Sweden.ORCID https://orcid.org/0000-0001-5923-5865
Ari LindqvistClinical Research Unit of Pulmonary Diseases, Helsinki University Hospital, Helsinki, Finland.
Helena BackmanDepartment of Public Health and Clinical Medicine, Section for Sustainable Health/the OLIN Unit, Umeå University, Umeå, Sweden.
Arnulf LanghammerHUNT Research Centre, Department of Public Health and Nursing, NTNU, Norwegian University of Science and Technology, Levanger, Norway.
Eva RönmarkDepartment of Public Health and Clinical Medicine, Section for Sustainable Health/the OLIN Unit, Umeå University, Umeå, Sweden.
Pinja IlmarinenDepartment of Respiratory Medicine, Seinäjoki Central Hospital, Seinäjoki, Finland.
Paula PallasahoWelfare and Health Sector, City of Espoo, Finland.
Päivi PiiriläUniversity of Helsinki, Helsinki, Finland.
University of Helsinki · FITampere University · FIUmeå University · SEFinnish Institute for Health and Welfare · FIKarolinska University Hospital · SENorwegian University of Science and Technology · NOSeinäjoki University of Applied Sciences · FI

Funding

Helsingin ja Uudenmaan SairaanhoitopiiriHengityssairauksien TutkimussäätiöIda Montinin SäätiöNordic Council of MinistersNummela Sanatorium FoundationTampereen TuberkuloosisäätiÖThe Competitive State Reseach Financing of the Expert Responsibility Area of Tampere University HospitalThe finnish anti-tuberculosis Association Foundationthe foundation of Väinö and laina kiviThe medical research fund of Seinäjoki Central HospitalWilhelm och Else Stockmanns Stiftelse
6 · The paper itself

Abstract

Smoking, exposure to environmental tobacco smoke (ETS) and occupational exposure to vapours, gases, dusts or fumes (VGDF) increase asthma symptoms. The impact of combined exposure is less well established. We aimed to evaluate the risk of combined exposure to smoking, ETS and VGDF on the prevalence of current asthma and asthma-related symptoms with a postal survey among a random population of 16,000 adults, aged 20-69 years (response rate 51.5%). The 836 responders with physician-diagnosed asthma were included in the analysis. Of them, 81.9% had current asthma defined as physician-diagnosed asthma with current asthma medication use or reported symptoms. There was a consistently increasing trend in the prevalence of current asthma by increased exposure. The highest prevalence of multiple symptoms was in smokers with VGDF exposure (92.1%) compared to the unexposed (73.9%, p = 0.001). In logistic regression analysis, combined exposure to several exposures increased the risk in all analysed symptoms (p = 0.002-0.007). In conclusion, smoking and exposure to ETS or VGDF increased the prevalence of current asthma and multiple symptoms. The combined exposure carried the highest risk. Preventive strategies are called for to mitigate exposure to tobacco smoke and VGDF.

Indexed as

AsthmaTobacco Smoke PollutionAdultAgedDustGasesHumansMiddle AgedNicotianaYoung AdultDustGasesTobacco Smoke PollutionasthmaETSexposuresmokingsymptomstobacco smokeVGDF

Identifiers

PMID35686373
PMCPMC9366564
OpenAlexW4281660463

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.