Evidence map›Paper›PMID 35686360›Full record

ArticleJournal of dental research2022

The Bone Sialoprotein RGD Domain Modulates and Maintains Periodontal Development.

K Nagasaki, M B Chavez, A Nagasaki, J M Taylor, M H Tan, M Ma, E Ralston, M E Thew, D-G Kim, M J Somerman and 1 more

Open access · greenAbstract read
In one paragraph

Article in Journal of dental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Functions of secretory calcium-binding phosphoproteins in dental mineralization.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2025
    Review
  8. Article
  9. The role of bone sialoprotein in bone healing.Journal of structural biology · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

K NagasakiLaboratory of Oral Connective Tissue Biology, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0003-0528-4025
M B ChavezBiosciences Division, College of Dentistry, The Ohio State University, Columbus, OH, USA.
A NagasakiLaboratory of Oral Connective Tissue Biology, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-7655-9658
J M TaylorLaboratory of Oral Connective Tissue Biology, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA.
M H TanBiosciences Division, College of Dentistry, The Ohio State University, Columbus, OH, USA.
M MaLaboratory of Oral Connective Tissue Biology, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA.
E RalstonLight Imaging Section, Office of Science and Technology, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA.
M E ThewDivision of Orthodontics, College of Dentistry, The Ohio State University, Columbus, OH, USA.
D-G KimDivision of Orthodontics, College of Dentistry, The Ohio State University, Columbus, OH, USA.
M J SomermanLaboratory of Oral Connective Tissue Biology, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA.
B L FosterBiosciences Division, College of Dentistry, The Ohio State University, Columbus, OH, USA.ORCID 0000-0003-3444-0576
National Institutes of Health · USThe Ohio State University · US

Funding

Comprehensive Training in Oral &Craniofacial SciencesT32DE014320 · NIDCR · OHIO STATE UNIVERSITY · PI SHERIDAN, JOHN F · 2001 to 2022
$10.2M
Functions of extracellular matrix proteins in dental and skeletal mineralizationR01DE027639 · NIDCR · OHIO STATE UNIVERSITY · PI Brian Lee Foster · 2019 to 2026
$2.3M
Functional domains of bone sialoprotein in dentoalveolar development and healingF30DE030358 · NIDCR · OHIO STATE UNIVERSITY · PI CHAVEZ, MICHAEL B. · 2021 to 2024
$198k
NIDCR NIH HHS F30 DE030358NIDCR NIH HHS R01 DE027639NIDCR NIH HHS T32 DE014320
6 · The paper itself

Abstract

Bone sialoprotein (gene:

Indexed as

Dental CementumIntegrin-Binding SialoproteinOligopeptidesAnimalsMicePeriodontal Ligamentarginyl-glycyl-aspartic acidIbsp protein, mouseIntegrin-Binding SialoproteinOligopeptidesbiomineralizationbonedental cementumextracellular matrixintegrinsperiodontium

Identifiers

PMID35686360
PMCPMC9403724
OpenAlexW4282009374

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.