Evidence map›Paper›PMID 35686192›Full record

ArticleInfection and drug resistance2022

Relationship Between Antibiotic Resistance, Biofilm Formation, and Biofilm-Specific Resistance in

Weidong Qian, Xinchen Li, Min Yang, Chanchan Liu, Yi Kong, Yongdong Li, Ting Wang, Qian Zhang

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
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  7. Veterinary sciences · 2025
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  9. Serrapeptase EliminatesMicroorganisms · 2025
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  11. Article
  12. Article
  13. Article
  14. Article
  15. A review of the mechanisms that confer antibiotic resistance in pathotypes ofFrontiers in cellular and infection microbiology · 2024
    Review
  16. Genetic landscape of ESBL producing international clone ST410 ofFrontiers in cellular and infection microbiology · 2024
    Article
  17. Biofilm Formation byMicroorganisms · 2023
    Article
  18. Article
  19. Incidence of biofilms among the multidrug resistant E. coli, isolated from urinary tract infections in the Nilgiris district, South India.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Weidong QianSchool of Food and Biological Engineering, Shaanxi University of Science and Technology, Xi'an, 710021, People's Republic of China.
Xinchen LiSchool of Food and Biological Engineering, Shaanxi University of Science and Technology, Xi'an, 710021, People's Republic of China.
Min YangSchool of Food and Biological Engineering, Shaanxi University of Science and Technology, Xi'an, 710021, People's Republic of China.
Chanchan LiuXi'an Medical College, Xi'an, 710309, People's Republic of China.
Yi KongResearch Center for Tissue Repair and Regeneration Affiliated to the Medical Innovation Research Department, the General Hospital of the People's Liberation Army, Beijing, 100048, People's Republic of China.
Yongdong LiNingbo Municipal Center for Disease Control and Prevention, Ningbo, 315010, People's Republic of China.
Ting WangSchool of Food and Biological Engineering, Shaanxi University of Science and Technology, Xi'an, 710021, People's Republic of China.
Qian ZhangDepartment of Dermatology, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, 518004, People's Republic of China.
Shaanxi University of Science and Technology · CNHuazhong University of Science and Technology · CNNingbo Center for Disease Control and Prevention · CNXi'an Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Several Methods: Antibiotic resistance/susceptibility profiles of 81 isolates from pediatric individuals in China between 2011 and 2014 against 20 antibiotics were assessed using the VITEK 2 system. Biofilm-forming capacities were evaluated using the crystal violet staining method, confocal laser scanning microscopy (CLSM), and field emission scanning electron microscopy. Biofilm compositions inside the biofilm formed by representative strains were assessed using CLSM. The effects of antibiotics on biofilms generated by Results: The results showed that 23 isolates were classified as multidrug-resistant, and 57 isolates were classified as extensively drug-resistant (XDR). Among the 69 isolates with the ability to form biofilms, 46 isolates were stronger biofilm formers. Correlation analysis demonstrated that strain populations exhibiting more robust biofilm formation likely contained larger proportions of XDR isolates. Conclusion: Together, our study implies that there was an association between biofilm-formation and resistance to several antibiotics for XDR-

Indexed as

antibiotic resistancebiofilmbiofilm-specific resistanceEscherichia coli

Identifiers

PMID35686192
PMCPMC9172925
OpenAlexW4281732566

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.