Evidence map›Paper›PMID 35686177›Full record

ArticleEFSA journal. European Food Safety Authority2022

Statement on safety of cannabidiol as a novel food: data gaps and uncertainties.

EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Jacqueline Castenmiller, Stefaan De Henauw, Karen Ildico Hirsch-Ernst, Alexandre Maciuk, Inge Mangelsdorf, Harry J McArdle, Androniki Naska and 25 more

Open access · diamondAbstract read
In one paragraph

Article in EFSA journal. European Food Safety Authority, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Safety ofEFSA journal. European Food Safety Authority · 2026
    Article
  4. Safety of cannabidiol isolated fromEFSA journal. European Food Safety Authority · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Safety of cannabidiol isolate fromEFSA journal. European Food Safety Authority · 2026
    Article
  9. Safety of carbon dioxide extract fromEFSA journal. European Food Safety Authority · 2026
    Article
  10. Update of the statement on safety of cannabidiol as a novel food.EFSA journal. European Food Safety Authority · 2026
    Article
  11. ComparativeFrontiers in toxicology · 2026
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Genotoxic assessment of aPharmaceutical biology · 2025
    Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors at 1 institution in 1 country.

EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA)
Dominique Turck
Torsten Bohn
Jacqueline Castenmiller
Stefaan De Henauw
Karen Ildico Hirsch-Ernst
Alexandre Maciuk
Inge Mangelsdorf
Harry J McArdle
Androniki Naska
Carmen Pelaez
Kristina Pentieva
Alfonso Siani
Frank Thies
Sophia Tsabouri
Marco Vinceti
Francesco Cubadda
Thomas Frenzel
Marina Heinonen
Rosangela Marchelli
Monika Neuhäuser-Berthold
Morten Poulsen
Miguel Prieto Maradona
Josef Rudolf Schlatter
Viviana Trezza
Henk van Loveren
Océane Albert
Céline Dumas
Andrea Germini
Wolfgang Gelbmann
Georges Kass
Eirini Kouloura
Estefania Noriega Fernandez
Annamaria Rossi
Helle Katrine Knutsen
Lille Inflammation Research International Center · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The European Commission has determined that cannabidiol (CBD) can be considered as a novel food (NF), and currently, 19 applications are under assessment at EFSA. While assessing these, it has become clear that there are knowledge gaps that need to be addressed before a conclusion on the safety of CBD can be reached. Consequently, EFSA has issued this statement, summarising the state of knowledge on the safety of CBD consumption and highlighting areas where more data are needed. Literature searches for both animal and human studies have been conducted to identify safety concerns. Many human studies have been carried out with Epidyolex

Indexed as

Cannabidioldata gapsNovel Foodsafety

Identifiers

PMID35686177
PMCPMC9172591
OpenAlexW4281896353

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.