Evidence map›Paper›PMID 35686143›Full record

ReviewOne health (Amsterdam, Netherlands)2022

Multidrug resistance from a one health perspective in Ethiopia: A systematic review and meta-analysis of literature (2015-2020).

Mebrahtu Tweldemedhin, Saravanan Muthupandian, Tsega Kahsay Gebremeskel, Kibrti Mehari, Getahun Kahsay Abay, Teklay Gebrecherkos Teklu, Ranjithkumar Dhandapani, Ragul Paramasivam, Tsehaye Asmelash

Erratum issuedOpen access · goldAbstract readReview
In one paragraph

Review in One health (Amsterdam, Netherlands), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
  7. Systematic review and meta-analysis ofOne health (Amsterdam, Netherlands) · 2025
    Review
  8. Article
  9. The Case for Genomic Surveillance in Africa.Tropical medicine and infectious disease · 2025
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Extended-spectrum beta-lactamase inOne health (Amsterdam, Netherlands) · 2023
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Mebrahtu TweldemedhinDepartment of Medical Microbiology and Immunology, College of Health Sciences, Mekelle University, Ethiopia.
Saravanan MuthupandianDepartment of Medical Microbiology and Immunology, College of Health Sciences, Mekelle University, Ethiopia.
Tsega Kahsay GebremeskelDepartment of Medical Microbiology and Immunology, College of Health Sciences, Mekelle University, Ethiopia.
Kibrti MehariDepartment of Medical Microbiology and Immunology, College of Health Sciences, Mekelle University, Ethiopia.
Getahun Kahsay AbayDepartment of Medical Microbiology and Immunology, College of Health Sciences, Mekelle University, Ethiopia.
Teklay Gebrecherkos TekluDepartment of Medical Microbiology and Immunology, College of Health Sciences, Mekelle University, Ethiopia.
Ranjithkumar DhandapaniChimertech Private Limited, Chennai, India.
Ragul ParamasivamChimertech Private Limited, Chennai, India.
Tsehaye AsmelashDepartment of Medical Microbiology and Immunology, College of Health Sciences, Mekelle University, Ethiopia.
Mekelle University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The emergence of antimicrobial resistance is a major global health challenge and becoming an urgent priority for policymakers. There is a paucity of scientific studies presenting the multidrug resistance pattern from one health perspective in Ethiopia. Therefore, a systematic review and meta-analysis aimed to determine the pooled prevalence of multidrug resistance in bacteria from human, animal, food, and environmental sources. Methods: In this systematic review and meta-analysis, an electronic search was made in PubMed & Google scholar using different keywords. The studies conducted in all areas of Ethiopia, published from 2015 to 2020 in peer-reviewed journals, English full-length papers were included. The meta-analysis was done on STATA version 14. The pooled prevalence of multidrug resistance for each bacterium was analysed using the random-effects model; Cochran Q statistics and the Results: 81 studies were included in the systematic review and meta-analysis; 53 human studies, eight animal studies, and 16 environments/food studies. The meta-analysis included six species from gram-positive bacteria and 13 from gram-negative bacteria. Conclusion: In Ethiopia, the pooled prevalence of MDR is high in most bacterial species from humans, animals, food, and environmental sources.

Indexed as

Antimicrobial resistancebacteriaCI, Confidence intervalCoNS, Coagulase-negative StaphylococciES, EstimateEthiopiaMDR, Multidrug resistanceMultidrug resistanceOne health

Identifiers

PMID35686143
PMCPMC9171526
OpenAlexW4224260723

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.